During V(D)J recombination, the coding ends to be joined are extensively modified. Those modifications, termed coding-end processing, consist of removal and addition of various numbers of nucleotides. We previously showed in vivo that coding-end processing is specific for each coding end, suggesting that specific motifs in a coding-end sequence influence nucleotide deletion and P-region formati...

Initiation of V(D)J recombination results in broken DNA molecules with blunt recombination signal ends and covalently sealed (hairpin) coding ends. In SCID mice, coding joint formation is severely impaired and hairpin coding ends accumulate as a result of a deficiency in the catalytic subunit of DNA-dependent protein kinase, an enzyme involved in the repair of DNA double-strand breaks. In this ...

the main idea of this survey was to gather the data related to malaysian open access journals (oajs) with respect to their subject, host organization, indexing, full text availability and language during 2005-2012. malaysian journals were selected for this survey because malaysia is currently one of the successful countries in science and technology among other islamic countries. data gathering...

Computer-aided content analyses programs have been deployed for social science research in recent years; however, few studies evaluated their effectiveness, compared to human coding. This study uses open-ended responses from respondents seeking information preparation Hurricane Michael compare human- and computer-coding. In particular, the comparison involves use of Excel as a common relatively...

The generation of political event data has remained much the same since the mid-1990s, both in terms of data acquisition and the process of coding text into data. Since the 1990s, however, there have been significant improvements in open-source natural language processing software and in the availability of digitized news content. This paper presents a new, next-generation event dataset, named ...