Hemolysins have been proven to be important virulence factors in many medically relevant pathogenic organisms. Their production has also been implicated in the etiology of periodontal disease. Hemolytic strain 361B of Prevotella melaninogenica, a putative etiologic agent of periodontal disease, was used in this study. The cloning, sequencing, and characterization of phyA, the structural gene fo...

Background: Atypical hemolytic uremic syndrome (aHUS) is a life-threatening and scarce disorder characterized by acute renal failure and disease, non-immune microangiopathic hemolytic anemia and thrombocytopenia, leading to end-stage renal failure or death, and consequently maybe accompanying by extra renal manifestations. Case report: We reported aHUS accompanied by autoimmune hemolytic anemi...

Several presumptive tests were evaluated for their effectiveness in differentiating streptococci. When the tests were combined into a battery and the resulting reactions were interpreted as patterns, the overall presumptive identification rate was at least 97%. We used the hemolytic reaction, susceptibility to bacitracin and sulfamethoxazole plus trimethoprim (1.25 micrograms plus 23.75 microgr...

BOUT a third of the patients with chronic lymphocytic leukemia develop hypogammaglobulinemia at some time or other during the course of their illness.’” The ensuing clinical manifestations are usually no different from those encountered in hypogammaglobulinemia from other causes; the patient may manifest an “immunologic paralysis” and is thereby rendered susceptible to infections of various kin...

Jablon, James M. (National Children's Cardiac Hospital, Miami, Fla.), Betty Brust, and Milton S. Saslaw. beta-Hemolytic streptococci with group A and type II carbohydrate antigens. J. Bacteriol. 89:529-534. 1965.-Ten strains of beta-hemolytic streptococci with unusual somatic antigens were isolated from excised tonsils or throat cultures or both. Acid extracts of these strains reacted with comm...

Formation dynamics of antibodies to rat erythrocytes (REs) and auto-antibodies to mouse erythrocytes were studied in an experimental model of autoimmune hemolytic anemia (AHA) in mice. The experimental conditions of AHA were simulated in a mathematical model of an immune network. It was found that maximal production of auto-antibodies and antibodies to REs do not synchronize. Antiserum, obtaine...

abstract background and objective: snake venom is a complex of several toxic elements and enzymes. it has the agents with the ability to destroy cellular and subcellular membrane and to bring about hemolysis of red blood cells (rbc). two types of direct and indirect hemolytic activity are known in snake venom in that phospholipase a2 is responsible for the indirect lysis. the aim of this study ...