fusion of two genes at dna level produces a single protein, known as a chimeric protein. immunotoxins are chimeric proteins composed of specific cell targeting and cell killing moieties. bacterial or plant toxins are commonly used as the killing moieties of the chimeric immunotoxins. in this investigation, the catalytic domain of shiga-like toxin (a1) was fused to human granulocyte macrophage c...

background : acanthamoeba castellanii forms a resistant cyst that protects the para-site against the host’s immune response. acanthamoeba type-i metacaspase (acmcp) is a caspase-like protein that has been found to be expressed during the encysta-tions. dictyostelium discoideum is an organism closely related to acanthamoeba useful for studying the molecular function of this protozoan caspase-lik...

conclusions data from this study about scla were not sufficient and further studies are needed; however, the information here suggests that scla could be a candidate for further research on the design of drugs and vaccines against s. pyogenes infections. results the scla protein is present on the cell surface of the cell and has interact with a common ligand by its hypervariable nh2-terminal re...