نتایج جستجو برای: paw edema test

تعداد نتایج: 855205  

2016
K. M. APARNA MANI C. VASANTHI DARLING CHELLATHAI DAVID

Phytostabilized silver nanoparticles are being widely studied for its various pharmacological properties. In the present study silver nanoparticles synthesized using Black pepper extract was evaluated for its acute toxicity and also for its anti inflammatory activity in carrageenan induced paw edema in rats. The anti inflammatory effect was also compared against the commercial silver nanopartic...

Amir Abbas Farshid Esmaeal Tamaddonfard, Leila Hosseini

Objective: Crocin, as an active constituent of saffron, has many biological functions including antioxidant and anti-inflammatory activities. The present study was aimed to investigate the effects of crocin and chlorpheniramine on local edema induced by histamine. Materials and Methods: Local edema was induced by subcutaneous injection of histamine (100 μl, 0.1%) in ventral surface of right hi...

Journal: :BMC Pharmacology 2001
Fábio Guilherme Gonçalves de Miranda Jeane Carvalho Vilar Ivana Andréa Nunes Alves Sócrates Cabral de Holanda Cavalcanti Ângelo Roberto Antoniolli

BACKGROUND Tabebuia avellanedae is a tree from the Bignoniaceae family. Commonly know as "pau d'arco" in Brazil, its inner bark is used as analgesic, anti-inflammatory, antineoplasic and diuretic at the Brazilian northeast. A validation of the plant usage has not been previously performed. RESULTS Antinociceptive and antiedematogenic effects of Tabebuia avellanedae Lor. ex Griseb. inner bark ...

2016
Ze Guo Hong-Yan Xu Lu Xu Sha-Sha Wang Xue-Mei Zhang

BACKGROUND Astragali Radix has long been used to improve immune function in traditional Chinese medicine. However, its main active components and potential immunomodulatory or anti-inflammatory activities have not been elucidated. In the present study, the immunomodulatory and anti-inflammatory activities of total flavonoids of Astragalus (TFA) isolated from Astragali Radix were evaluated by us...

Journal: :Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2012
Valiollah Hajhashemi Behzad Zolfaghari Abbas Yousefi

OBJECTIVE The aim of this study was to evaluate the anti-inflammatory and analgesic effects of Satureja hortensis seed extracts and to analyze their essential oil constituents. MATERIALS AND METHODS Hydroalcoholic and polyphenolic extracts and essential oil of S. hortensis seeds were prepared using standard methods. Analgesic activity was assessed in male mice (25-35 g) using standard methods...

2014
Lili Wen Yang Huang Xianbiao Xie Wan Huang Junqiang Yin Wenqian Lin Qiang Jia Weian Zeng

The aims of this study were to evaluate the anti-inflammatory and analgesic effects of bufalin, a major component of "Chan-su." We used a carrageenan-induced paw edema model to assess the anti-inflammatory activity of this compound, and Western blot analysis detected NF- κ B signaling during this effect. The antinociceptive activities were evaluated by acetic acid-induced writhing, formalin, an...

2018
Ibrahim M. El-Ashmawy

Many species of Teucrium were used traditionally in treatment of inflammatory disorders. The present study aimed to assess the anti-inflammatory effect of methanolic extract of aerial parts of Teucrium oliverianum Ging. ex. Benth. (family, Lamiaceae). The extract was evaluated using the carrageenan-induced rat paw edema (Acute and sub-acute models), and turpentine oil–induced granuloma pouch bi...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - دانشکده داروسازی 1392

داروهای ضدالتهاب غیراستروئیدی یکی از پر مصرف ترین گروه های دارویی در درمان درد و التهاب و تب مطرح هستند. اما عوارض جانبی آنها از جمله عوارض گوارشی و کلیوی استفاده از این داروها را محدود می کند. یکی از مهمترین عوامل در ایجاد این عوارض جانبی، مهار آنزیم های سیکلواکسیژناز و سنتز پروستاگلاندین های محافظ می باشد، علاوه بر این،اثرات مخرب برخی از داروهای nsaids بر دستگاه گوارش ناشی از طبیعت اسیدی آنها...

Journal: :Phytomedicine : international journal of phytotherapy and phytopharmacology 2011
L K A M Leal T M Pierdoná J G S Góes K S Fonsêca K M Canuto E R Silveira A M E Bezerra G S B Viana

The objectives of this work were to carry out a comparative chemical study and to evaluate the antinociceptive and anti-inflammatory activities of ethanol extracts (EtOHE) and vanilic acid (VA) from cultivated and wild Amburana cearensis A.C. Smith (Fabaceae), an endangered species used in Northeast Brazil for the treatment of asthma. The HPLC analysis of EtOHE, showed that coumarin (CM) and VA...

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