Isoniazid chemoprophylaxis is not recommended for all persons infected with tubercle bacilli. Because of the small but significant risk of isoniazid hepatotoxicity, chemoprophylaxis is reserved for only those at the highest risk of tuberculosis activation. To evaluate this policy, we performed a cost-effectiveness analysis of isoniazid chemoprophylaxis for two populations with positive tubercul...

Aim: The aim of this study was to investigate the incidence of bovine tuberculosis (BTB), an old chronic disease having zoonotic potential, covering four districts in Gangetic delta region of West Bengal, India, and to find the prevalence in organized as well as backyard herds and variation in relation to their age, sex, and breeds. Methods: The incidence of BTB in exotic and indigenous breeds ...

Several studies have demonstrated an elevated prevalence amongst professionals of mycobacterium tuberculosis, both in the rate of infections and illness. This study was carried out in a School Hospital in Campo Grande, MS, Brazil, aiming to establish the prevalence of infection with Mycobacterium tuberculosis. The results of the analysis of 194 subjects showed an overall positivity for the tube...

he marked annual decrease in the number of Tnewly reported cases of active tuberculosis during the past ten years has been accompanied by a similar decreased effectiveness of chest x-ray mass screening as a tool in community tuberculosis casefinding programs. However, during the same period, tuberculin skin testing of pre-school and school age children, followed by a thorough examination of pos...

Infectivity of Sputum smear positive patients with tuberculosis for household contacts was assessed before diagnosis and during domiciliary treatment. Intracutaneous tuberculin test, sputum and radiological examinations were done in all cases and their house-hold contacts initially; and were repeated for contacts every six months during two years follow-up. Initially 244 (56%) contacts gave pos...