BACKGROUND Protein misfolding is usually deleterious for the cell, either as a consequence of the loss of protein function or the buildup of insoluble and toxic aggregates. The aggregation behavior of a given polypeptide is strongly influenced by the intrinsic properties encoded in its sequence. This has allowed the development of effective computational methods to predict protein aggregation p...

The main objective of the current study was to analyze the proximate composition and the amino acid profile of the Persian sturgeon (Acipenser persicus). Forty-eight fish (with an initial weight of 96.60   7.45 g) were randomly sampled from a local sturgeon farm in Mazandaran, Iran. The proximate analysis of the fish body showed 24.38 ± 1.62 g/100g ww of dry matter, 61.52 ± 1.65 g/100g dw of cr...

conclusions these results show the usefulness of proteome analysis in successful identification of the common proteins between n. lactamica strains and nmb. this proteomics analysis is the starting point in the path of knowledge development about whole proteome profiles of n. lactamica strains. objectives the main aims of this study were to determine whole proteome profiles of n. lactamica stra...

Background and Objectives: Diabetes vascular complications are the principal cause of death in the world. Therefore, we investigated the effect of pyridoxal phosphate (PLP) on the formation of atheromatous plaque formation and renal function in the atherosclerotic rats. Materials and Methods: Male Wistar rats were randomly divided into 4 equal groups (ten rats in each group): normal, ath...

Objective: Oxidative stress leads to reactive oxygen species (ROS) overproduction, which causes tissue injury in diabetic patients. The aim of this study was to evaluate the effects of Zataria multiflora extract on TNF-α, oxidative stress products, and insulin levels as well as lipid profile in diabetic rats. Materials and Methods: Rats were randomly divided into 6 groups of 10 animals. Diabete...

Proteins often exist as their multimeric forms when they function as so-called biological assemblies consisting of the specific number and arrangement of protein subunits. Consequently, elucidating biological assemblies is necessary to improve understanding of protein function. Template-Based Modeling (TBM), based on known protein structures, has been used widely for protein structure predictio...

Abstract There is evidence for the beneficial effects of forage peanut on nutritive value and fermentation profile silages; however, its sugarcane silage have not been determined. The objective study was to evaluate chemical composition, profile, microbial dry matter recovery (DMR) containing various amounts (Arachis pintoi cv. Belmonte) (0%, 25%, 50%, 75% a fresh basis), treated or untreated w...