abstract  introduction: diabetes mellitus is the most common metabolic and endocrine disease. depressed heart rate variability (hrv) is an early warning sign of diabetic neuropathy. in numerous studies, spironolactone improved hrv and decreased mortality in congestive heart failure (chf). this study was performed to assess the effect of spironolactone on hrv in diabetic patients. methods: this ...

This study aimed to develop and assess the effectiveness of a web-based nutrition education program for self-managing IBS symptoms using IMB model. used single-arm, pre–post design test after its development. Participants were adults in their twenties thirties South Korea with according ROME IV diagnostic criteria (n = 49). For statistical analysis, normality was verified Shapiro–Wilk test, var...

The Wilcoxon rank-sum test is widely used to test the equality of two populations, because it makes fewer distributional assumptions than parametric procedures such as the t-test. However, the Wilcoxon rank-sum test can be used only if data are independent. When data are clustered, tests based on generalized estimating equations (GEEs) that generalize the t-test have been proposed. Here we deve...

Results: All measurements were pooled and submitted to statistical analysis. In order to verify the inter-examiner systematic error a paired t-test was performed. Dahlberg ’s formula was used to estimate the casual error. For comparison purposes between Before and After stages, a paired t-test was done. For the comparison between mini-implant and Nance button groups, a Student t-test was applie...