objective(s): we examined the effects of endurance exercise in the presence of bunium persicum extract administration on lipid profile and cardiorespiratory capacity in hypercholesterolemic male mice. materials and methods: forty male hypercholesterolemic mice were divided into four groups: vehicle, endurance exercise (ee), bunium persicum extract (bpe), and ee + bpe. the exercise protocol was ...

The purpose of the current study was to investigate the effect of a high- intensity treadmill running (8 weeks) with or without aqueous extraction of black Crataegus-Pentaegyna (Siyah -Valik) on liver ABCA1 mRNA expression and plasma HDL-C, total, and direct bilirubin concentration in male rats. Twenty Wistar male rats (4-6 weeks old, 140-170 g weight) were used. Animals were randomly assigne...

Objective(s) We investigated the effects of low-dose morphine on nitric oxide (NO) and angiogenesis in two-kidney one clip hypertensive (2K1C) rats. Materials and Methods Male rats were divided into two groups: sham-clip operated and 2K1C. Each group subdivided into saline and morphine (3 mg/kg i.p. 8 weeks) groups. Blood pressure, heart rate, plasma renin activity (PRA), NO concentration an...

We tested the hypothesis that renal tubular Na(+) reabsorption increased during the first 24 h of exercise-induced plasma volume expansion. Renal function was assessed 1 day after no-exercise control (C) or intermittent cycle ergometer exercise (Ex, 85% of peak O(2) uptake) for 2 h before and 3 h after saline loading (12.5 ml/kg over 30 min) in seven subjects. Ex reduced renal blood flow (p-ami...

OBJECTIVE To verify the functionality through muscle grip strength in animals with obesity induced by monosodium glutamate (MSG) and in control animals, which suffered compression of the right median nerve, and treated with swimming with overload. METHODS During the first five days of life, neonatal Wistar rats received subcutaneous injections of MSG. The control group received a hypertonic s...

Amphetamines exert their persistent addictive effects by activating brain's reward pathways, perhaps through the release of dopamine in the nucleus accumbens (and/or in other places). On the other hand, there is a relationship between dopamine and all behavioural aspects that involve motor activity and it has been demonstrated that exercise leads to an increase in the synthesis and release of d...

conclusions it seems that the concept of negative-calorie lacks any validity and application. contrary to expectation, efficacy of both weight-loss diets was the same. patients and methods this was a randomized study (the consort statement) carried out at ukrainian center of sports medicine (kiev-2012). participants (n = 66) included sedentary overweight or obese women (age 45-64 years). they w...