Saffron, the dried red-orange stigmas of Crocus sativus L, has been known as a flavoring agent, food coloring and traditional herbal medicine. Pharmacological effects of saffron are mainly attributed to crocin, crocetin, picrocrocin and safranal. These components especially crocin, have significant effects including antidepressant and anticonvulsant, analgesic, anti-cancer and other therapeutic...

conclusions combination therapy with tretinoin plus topical corticosteroids is safe and effective and provides an alternative in the treatment of patients with vitiligo. objectives recent studies suggest that administration of topical tretinoin, with a corticosteroid, diminishes skin atrophy without impacting the steroid’s anti-inflammatory effects. patients and methods a placebo-controlled, pa...

results researchers have reported that mirnas can repress the expression of important cancer-related genes and might be helpful in the diagnosis and treatment of cancer. during the past two decades, numerous studies have shown that mirnas play an essential role in inhibiting hcc via several different pathways. deregulated mirnas may contribute to carcinogenesis, indicating that mirnas can act a...

an experiment was conducted on eight weak and anaemic goats revealed pale conjunctivae, increased heart rate, rough hair coat, dullness and depression. the haematology showed significantly decreased haemoglobin (7.37±0.16 g %), packed cell volume (pcv)(23.37±0.56%),total erythrocyte count (tec)(8.12±0.18 million/cumm), mean corpuscular haemoglobin (mch) (9.10±0.30 pg) and mean corpuscular volum...

Background: Acoustic cavitation which occurs at high intensities of ultrasound waves can be fatal for tumor cells; however, it can be used to destroy cancer cells as an efficient therapeutic method. On the other hand, it is known that the existence of nanoparticles in a liquid decreases the acoustic cavitation onset threshold. Materials and Methods: In this work, the combined effects of therape...

background: saffron (crocus satious l.) provides a variety of promising preventive and therapeutic effects with non-considerable side effects. objective: based on our knowledge, this is the first study that simultaneously has reviewed the effect of saffron extract and its constituents on the factors associated with neuropsychological, cardiovascular, and gastrointestinal tract diseases. methods...