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Alireza Rezaee Khorasany

Pharmaceutical Research Center, Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

[ 1 ] - Therapeutic effects of saffron (Crocus sativus L.) in digestive disorders: a review

Saffron, the dried red-orange stigmas of Crocus sativus L, has been known as a flavoring agent, food coloring and traditional herbal medicine. Pharmacological effects of saffron are mainly attributed to crocin, crocetin, picrocrocin and safranal. These components especially crocin, have significant effects including antidepressant and anticonvulsant, analgesic, anti-cancer and other therapeutic...

[ 2 ] - Effect of crocin, an active saffron constituent, on ethanol toxicity in the rat: histopathological and biochemical studies

<em><strong>Objective(s):</strong></em> The drinking of ethanol causes the wide range of clinical illness and morphological changes including hepatotoxicity and nephrotoxicity. In the current study, the protective properties of crocin versus oxidative stress, apoptosis and inflammation induced by ethanol were assessed. <br /><em><strong>Materials and Methods:</strong> </em>The male Wistar rats ...