Cerebral ischemia leads to brain injury via a complex series of pathophysiological events. Therefore, multidrug treatments or multitargeting drug treatments are attractive options in efficiently limiting brain damage. Here, we report a novel multifunctional compound oxopropanoyloxy benzoic acid (OBA-09), a simple ester of pyruvate and salicylic acid. This protective effect was manifested by rec...

The aim of this paper is two-fold: first, it is intended to articulate theses that are often assessed independently, thus showing that a strong version of epistemological disjunctivism about perceptual knowledge implies a transformative conception of rationality. This entails that individuals in skeptical scenarios could not entertain rational thoughts about their kriterion, Belo Horizonte, no ...

BACKGROUND AND OBJECTIVE Inhaled glucocorticoids and long acting β2 -agonists reduce airway inflammation. It is unclear if this effect is based on the local action of the drugs or is due to a systemic effect on circulating peripheral blood lymphocytes. We assessed whether inhaled budesonide and/or formoterol modify the activity of circulating peripheral blood lymphocytes. METHODS Placebo cont...

Three new direct-service staff participated in a program that used a video model to train target skills needed to conduct a discrete-trial session. Percentage accuracy in completing a discrete-trial teaching session was evaluated using a multiple baseline design across participants. During baseline, performances ranged from a mean of 12% to 63% accuracy. During video modeling, there was an imme...

BACKGROUND The human ability to envision the future, that is, to take a future perspective (FP), plays a key role in the justice motive and its function in transcending disadvantages and misfortunes. The present research investigated whether individual (Study 1) and situational (Study 2) differences in FP moderated the association of general belief in a just world (GBJW) with psychological resi...

OBJECTIVE To examine the opinions of Libyan doctors regarding the quality of drug information provided by pharmaceutical company representatives (PCRs) during detailing visits. METHOD An anonymous survey was conducted among 1,000 doctors from selected institutes in Tripoli, Benghazi and Sebha. Doctors were asked questions regarding the quality of information provided during drug-detailing vis...

Abstract Specific scope This Standard defines how the dose of plant protection products should be expressed, and describes different expression terms their interconversion. It also parameters, specific to crop, site type application, which recorded so that applied can determined in a standard way whatever crop or product, equipment used for treatment. includes definitions common description (Ap...