Introduction: Cell transplantation is one of the main strategies for spinal cord injury repair. As OECs of the olfactory mucosa can be obtained by simple biopsy in all individuals without affecting their smell sensation, OECs considered as a promising candidate for autologous transplantation in the nervous system injury, especially for spinal cord repair. Thereby in the current study OECs wer...

introduction: iiron oxide nanoparticles (io np) have an increasing number of biomedical applications. to date, the potential cytotoxicity of these particles remains an issue of debate. little is known about the cellular interaction or toxic effects of io np on differentiation of stem cells. the aim of the present study was to investigate the possible toxic role of different doses of io np in di...

Background and Aims: Total hip arthroplasty (THA) is a common orthopedic surgery. The main focus in the research of THA is immune responses in these patients following the blood transfusion.Therefore, in this study, we evaluated the immune modulation indexes such as T cell amplification, Tcell surface markers and also production of cytokines in the patients undergoing THA surgery following bloo...

objective: the properties of self-renewal and divisionin spermatogonial stem cells (sscs) support spermatogenesis. there are a number of reported methods for in vitro ssc culture systems. the development of a culture system that effectively supports isolation and self-renewal ofgermline stem cells (gscs) is of tremendous benefit for clinical trials, experimental research andas potential treatme...

Background: The recent improvements in wound healing have led to new strategies in regenerative medicine. Burn wound healing is an important issue in skin regeneration and has multiple indications for stem cell therapy. Hair follicle stem cells (HFSCs) are a highly promising source of stem cells for healing use, as these cells are accessible, active and pluripotent adult stem cells. Methods: HF...

Strategies of Schwann cell (SC) transplantation to regenerate the peripheral nerve injury involves many limitations. Stem cells can be used as alternative cell sources for differentiation into SCs. Given the high potential of neural crest-derived stem cells for the generation of multiple cell lineages, in this research, we considered whether olfactory ecto-mesenchymal stem cells (OE-MSCs) derive...

in the last few years, a lot of preclinical studies showed the therapeutic potential of stem cells in spinal cord injury (sci). neural stem cells (nscs) can be differentiated into all cell types of spinal cord. nscs are cells that maintain the capacity to differentiate into brain-specific cell types, and may also replace or repair of injury in central nervous system. here in, we describe the ef...

purpose: to assess the histopathological and immunohistochemical features of orbital spindle cell tumors. methods: a descriptive, retrospective study was performed on 63 pathology reports on all types of orbital spindle cell tumors at the pathology department of farabi hospital between 1995 and 2005. immunohistochemistry studies for different markers, such as smooth muscle actin, desmin, s100 p...