introduction atmospheric circulation patterns leads to different weather conditions and rainfall regime change is controlled by seasonal and irregular variations of atmospheric circulation pattern. variety and climate change, such as drought and flood result in changes in the spatio-temporal of precipitation, one of the important parameters conditions mentioned, heterogeneity in moisture transm...

Within the present study we shed light on the question whether objective circulation patterns (CP) classified from either the 500 HPa or the 700 HPa level may serve as predictors to explain the spatio-temporal variability of monsoon rainfall in the Anas catchment in North West India. To this end we employ a fuzzy ruled based classification approach in combination with a novel objective function...

Autosomal dominant polycystic kidney disease (ADPKD) is a commonly inherited renal disorder caused by defects in the PKD1 or PKD2 genes. ADPKD is associated with significant morbidity, and is a major underlying cause of end-stage renal failure (ESRF). Commonly, treatment options are limited to the management of hypertension, cardiovascular risk factors, dialysis, and transplantation when ESRF d...

introduction dust storms, one type of dust event, are in most cases the result of turbulent winds, including convective haboobs, which raise large quantities of dust from desert surfaces and reduce visibility to less than 1 km. this dust reaches concentrations in excess of 6000 mg m3 in severe events. the major dust source regions are areas of arid and hyper-arid, with mean annual rainfalls of ...

Protein synthesis and its fidelity rely upon the aminoacyl-tRNA synthetases. Leucyl-tRNA synthetase (LeuRS), isoleucyl-tRNA synthetase (IleRS), and valyl-tRNA synthetase (ValRS) have evolved a discrete editing domain called CP1 that hydrolyzes the respective incorrectly misaminoacylated noncognate amino acids. Although active CP1 domain fragments have been isolated for IleRS and ValRS, previous...