Abstract We aim to identify predictors of tumor dynamics during radiotherapy for glioblastoma. METHODS: This is a prospective serial MRI study in patients with MRIs were obtained at planning (F0), fraction-10 (F10), and fraction-20 (F20). The metrics (relative F0) assessed included: relative gross volume (GTV) changes (Vrel) migration distance (dM). RESULTS: 129 included this study. Median GTV ...

Chaharmahal and Bakhtiari province is a most important endemism states of flora of Iran with a considerable plant species diversity in the country. In the present study the cytotoxic activity of 13 plant species grown in Chaharmahal and Bakhtiari have been evaluated on prostate (PC-3), breast (MCF-7), liver (HepG2), ovary (CHO) and melanoma (B16-F10) cancer cell lines. The cytotoxicity and apop...

UNLABELLED Previously, we reported a small-molecular-weight peptide, single amino acid chelae((99m)Tc)-conjugated phosphatidylserine-binding peptide (SAAC((99m)Tc)-PSBP-6), with high binding affinity to phosphatidylserine on the surface of apoptotic cells. The purpose of this study was to determine the effectiveness of SAAC((99m)Tc)-PSBP-6 in detecting apoptosis induced by chemotherapy. METHO...

B16/F10 melanoma cells, in a medium containing fibrinogen, form a coating of fibrin(ogen) on their surfaces. This coating is cross-linked in a manner characteristic of catalysis by cellular transglutaminase. The fibrin(ogen) coating on the surface of these tumor cells provides protection against the lytic effect of autologous lymphokine-activated killer cells.

Background. The effectiveness of cancer neoantigen peptide vaccines depends on the presence an adjuvant in their composition. Poly(I:C), a TRL-3 agonist, is used as mouse models vaccines, but has limitations for use humans. Therefore, search new effective adjuvants inclusion composition vaccine relevant. Ridostin Pro domestic drug that contains natural complex sodium salts double-chiral and sin...