نتایج جستجو برای: formation of new memories

تعداد نتایج: 21398717  

2015
A Iván Hernández Juan M Alarcon Kim D Allen

Widely thought to be a housekeeping process, the regulation and synthesis of rRNA emerges as a potentially central mechanism for the maintenance of synaptic plasticity and memory. We have recently shown that an essential component of late-phase synaptic plasticity is rRNA biosynthesis - the rate-limiting step in the production of new ribosomes. We hypothesize that a particular population of rib...

2017
Yoshio Hoshiba Takeyoshi Wada Akiko Hayashi-Takagi

Memories are crucial to the cognitive essence of who we are as human beings. Accumulating evidence has suggested that memories are stored as a subset of neurons that probably fire together in the same ensemble. Such formation of cell ensembles must meet contradictory requirements of being plastic and responsive during learning, but also stable in order to maintain the memory. Although synaptic ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2001
K M Lattal T Abel

Many molecular accounts of long-term memory storage postulate that the synthesis of new proteins is necessary for long-term changes in neuronal function. These experiments generally have examined the learning that occurs as associations are acquired between neutral and biologically important stimuli. Little is known about the importance of protein synthesis in the establishment of memories for ...

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2013
Nathan C Keim Joseph D Paulsen Sidney R Nagel

Multiple transient memories, originally discovered in charge-density-wave conductors, are a remarkable and initially counterintuitive example of how a system can store information about its driving. In this class of memories, a system can learn multiple driving inputs, nearly all of which are eventually forgotten despite their continual input. If sufficient noise is present, the system regains ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علامه طباطبایی 1388

foreign policy takes root from complicated matters. however, this issue may be more truth about armenia. although the new government of armenia is less than 20 years, people of this territory are the first ones who officially accepted christianity. in very past times, these people were a part of great emperors like iran, rome, and byzantium.armenia is regarded as a nation with a privileged hist...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه یزد - دانشکده زبانهای خارجی 1391

the speech act of disagreement has been one of the speech acts that has received the least attention in the field of pragmatics. this study investigates the ways power relations, social distance, formality of the context, gender, and language proficiency (for efl learners) influence disagreement and politeness strategies. the participants of the study were 200 male and female native persian s...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه یاسوج - دانشکده ادبیات و علوم انسانی 1392

an investigation into oral interaction in language classes: a conversation analytic point of view the aim of this thesis is to analyze the interaction between language teachers and students in english language institutes. this work is done in the context of yasuj city. learning another language, which is in most cases english, involves many variables. one of these variables is the linguistic...

2016
Cynthia Katche Micol Tomaiuolo Guido Dorman Jorge H. Medina Haydee Viola

Learning to avoid threats in the environment is highly adaptive. However, sometimes a dysregulation of fear memories processing may underlie fear-related disorders. Despite recent advances, a major question of how to effectively attenuate persistent fear memories in a safe manner remains unresolved. Here we show experiments employing a behavioural tool to target a specific time window after tra...

Journal: :Proceedings of the National Academy of Sciences 2009

Journal: :Science 2014
Katherine G Akers Alonso Martinez-Canabal Leonardo Restivo Adelaide P Yiu Antonietta De Cristofaro Hwa-Lin Liz Hsiang Anne L Wheeler Axel Guskjolen Yosuke Niibori Hirotaka Shoji Koji Ohira Blake A Richards Tsuyoshi Miyakawa Sheena A Josselyn Paul W Frankland

Throughout life, new neurons are continuously added to the dentate gyrus. As this continuous addition remodels hippocampal circuits, computational models predict that neurogenesis leads to degradation or forgetting of established memories. Consistent with this, increasing neurogenesis after the formation of a memory was sufficient to induce forgetting in adult mice. By contrast, during infancy,...

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