mdma generally known as ecstasy, have deleterious effects on the serotonergic neurotransmitter system. recent findings suggest that the liver and brain are major target organs of mdma-related toxicities. although most research is being dynamically performed on brain, however, the molecular mechanisms by which mdma elicits adverse effects in both organs are poorly undrestood.the present study wa...

background 3-4methylenedioxymethamphetamine (mdma) is a synthetic and psychoactive drug, which is known popularly as ecstasy and has toxic effects on human organs. objectives considering the potential toxic interaction, this study was performed to quantify the expression of bax and bcl2 genes in mdma-induced hepatotoxicity on rat liver. subsequently, we evaluated pentoxifylline as a possible pr...

The basis, and characterization, of pro-poor growth remain a source of debate in the current development literature. The paper sheds light on this debate with an example drawn from an analysis of household panel data from Bangladesh. The objective is to determine if observed rural income growth and the policies supporting this growth have been pro-poor — that is, whether policies and growth hav...

backgrounds and aims: p53 gene is regarded important in pathogenesis of different cancers. therefore, this study aimed to investigate the frequency of p53 gene codon 72 arg/pro polymorphism in women suffering from breast cancer. materials and methods: a total of 90 patients with breast cancer and 83 matched healthy control women participated in this case-control study. genomic dna was extracted...

introduction: the molecular mechanisms involved in pathogenesis of esophageal cancer have been the main concern of several studies. in this study, we aimed to investigate the changes of serum prooxidant-antioxidant balance (pab) value as a redox index, as well as serum c-reactive protein (crp) compared to healthy control group. materials and methods: in a cross-sectional study, blood samples we...