The HCOOH molecule represents the simplest organic acid which is also supposed to play a role in the interstellar formation of more complicated biomolecules. Its interaction with slow electrons in the gas phase is analysed in the present work with the view of providing specific structural and dynamical information on those resonant states which lead to different transient negative ions (TNIs) f...

Objective: Purposes of this work were i) to develop an in silico model tumor response radiotherapy, ii) perform exhaustive sensitivity analysis order iii) propose a simplified version and iv) predict biochemical recurrence with both the comprehensive reduced model. Methods: A multiscale computational radiotherapy was developed. It integrated following radiobiological mechanisms: oxygenation, in...

There are radiobiological rationales supporting hypofractionated radiotherapy for prostate cancer. The recent advancements in treatment planning and delivery allow sophisticated radiation treatments to take advantage of the differences in radiobiology of prostate cancer and the surrounding normal tissues. The preliminary results from clinical studies indicate that abbreviated fractionation prog...

PURPOSE Permanent low-dose-rate (LDR-BT) and temporary high-dose-rate (HDR-BT) brachytherapy are competitive techniques for clinically localized prostate radiotherapy. Although a randomized trial will likely never to be conducted comparing these two forms of brachytherapy, a comparative analysis proves useful in understanding some of their intrinsic differences, several of which could be exploi...