نتایج جستجو برای: adenocarcinoma model

تعداد نتایج: 2160478  

Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. Methods: In the current cr...

In the recent years deregulation for microRNAs expression pattern have emerged as a possible molecular factor for carcinogenesis. It has been reported that the expression of miR-9 was down-regulated in human gastric adenocarcinoma. To figure out the molecular mechanism of this down regulation, the methylation status in promoters of miR-9 family loci were compared in the human gastric adenocarci...

ژورنال: Hormozgan Medical Journal 2012
Farajian Abbasi, M. , Mousavi, S.A. , Zare, S. ,

Introduction: Prostatic adenocarcinoma is one the most common malignances and the second cause of death in males due to cancer. Prostate Specific Antigen (PZSA) serum level is the first marker to screen such patients. We aimed in this study, to assess the intensity of prostatic adenocarcinoma tissue staining with PSA staining method. Methods: In this corss-sectional study, prostatic adenocarcin...

PARVIN KHERADMAND, SIMIN TORABI-NEZHAD,

Thirty cases of benign prostatic hyperplasia and 30 cases of prostatic adenocarcinoma were selected and stained by AgNOR (argyrophilic staining of the nucleolar organizer region) method. Specimens were obtained by either prostatectomy (open!TIJR) or needle biopsy of the prostate. In this study, the sections of prostatic adenocarcinoma were reviewed. 6 cases were diagnosed as well-differen...

Abolhasani, Maryam , Angaji, Seyed Abdolhamid , Beikzadeh, Behnaz ,

Background and Objective: Prostate cancer is among the five common cancers in males. It is second cancer in terms of the age-standardized rate (ASR) (ASR=16.6) in Iran. The rs2735839 G/A, an intergenic polymorphism is located on chromosome 19q13.33 at 600 base pairs of the KLK3 gene untranslatable region. This gene which codes prostate-specific antigen (PSA) is used in the screening and diagnos...

Background and Objective: Early diagnosis of malignant pleural mesothelioma (MPM) is the key point of its treatment. The main problem is the precise diagnosis of mesothelioma and its differentiation from metastatic lung adenocarcinoma. Mesothelioma exhibits complex immunohistochemical characteristics. The aim of this study was to study hybrid immunohistochemistry in the differe...

Journal: :journal of biotechnology and health sciences 0
reza najafipour cellular and molecular research center, qazvin university of medical sciences, qazvin, ir iran taghi naserpour farivar cellular and molecular research center, qazvin university of medical sciences, qazvin, ir iran; cellular and molecular research center, qazvin university of medical sciences, qazvin, ir iran. tel/fax: +98-2813324971 pouran johari cellular and molecular research center, qazvin university of medical sciences, qazvin, ir iran

background gastric cancer is the second most common cause of cancer death worldwide. lentinan was shown to induce apoptosis in gastric cancer cells and could be used for the treatment of gastric cancer. objectives in this study, we analyzed anticancer effect of lentinan, a fungal β-glucan, on the gastric adenocarcinoma cell line (ags). materials and methods we used the dna ladder and tunnel app...

Journal: :middle east journal of cancer 0
gamal abdul hamid hematology-oncology department, al-gamhouria teaching hospital, aden, yemen nohad hanbala pathology department, faculty of medicine, university of aden, aden, yemen

cutaneous metastases of rectal carcinoma is a rare event. it occurs in fewer than 4% of all patients with rectal cancer. when present, it typically signifies a disseminated disease with a poor prognosis. early detection and proper diagnosis of metastatic rectal cancer can significantly alter treatment and prognosis. we report a 70-year-old male who underwent rectal resection with permanent colo...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Jin-Yuan Shih Meng-Feng Tsai Tzu-Hua Chang Yih-Leong Chang Ang Yuan Chong-Jen Yu Shin-Bey Lin Geou-Yarh Liou Meng-Larn Lee Jeremy J W Chen Tse-Ming Hong Shuenn-Chen Yang Jen-Liang Su Yung-Chie Lee Pan-Chyr Yang

PURPOSE In a previous genome-wide gene expression profiling analysis using an invasion cancer cell lines model, we have identified Slug as selectively overexpressed in the highly invasive cancer cells. Here, we investigated the clinical significance of Slug in lung adenocarcinoma and the role of Slug in the process of cancer cell invasion and metastasis. EXPERIMENTAL DESIGN Real-time quantita...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Masood A Shammas Aamer Qazi Ramesh B Batchu Robert C Bertheau Jason Y Y Wong Manjula Y Rao Madhu Prasad Diptiman Chanda Selvarangan Ponnazhagan Kenneth C Anderson Christopher P Steffes Nikhil C Munshi Immaculata De Vivo David G Beer Sergei Gryaznov Donald W Weaver Raj K Goyal

PURPOSE The aims of this study were to investigate telomere function in normal and Barrett's esophageal adenocarcinoma (BEAC) cells purified by laser capture microdissection and to evaluate the effect of telomerase inhibition in cancer cells in vitro and in vivo. EXPERIMENTAL DESIGN Epithelial cells were purified from surgically resected esophagi. Telomerase activity was measured by modified ...

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