CONTEXT In 1997, unintentional injury was the leading cause of death for persons aged 1 to 34 years. Approximately one third of deaths due to unintentional injury in the United States are estimated to be alcohol related. Onset of drinking at an early age has been found to be associated with alcohol dependence, but whether early-onset drinking increases risk for unintentional injury while drinki...

A recurring theme in the tourism literature is how travelers and tourism businesses perceive the concept of diversity and uniqueness of attractions pinned to places called tourism destinations and respond to their perceptions. In this backdrop, the primary focus of this research is a reexamination of the unique selling proposition (USP) based tourism marketing practice that various Caribbean is...

BACKGROUND Prenatal alcohol exposure may be a risk factor for the development of alcohol problems in humans. METHODS We use data beginning with interviews of women in prenatal care at midpregnancy to predict alcohol use and alcohol-related problems in their offspring now aged 21 years. Maternal drinking during pregnancy was assessed from November 4, 1974, through October 2, 1975, along with m...

OBJECTIVES AND METHODS To investigate the impact of prenatal diagnosis on trisomy 21 live births, we collected all prenatal and postnatal trisomy 21 cases (n = 1096) in the eastern half of Switzerland for the years 1980-1996. RESULTS Despite increasing prenatal detection rates of trisomy 21 foetuses (an increase of 169% in the last 5 versus the first 5 years of the study period) and subsequen...

The true incidence and prognosis of autoimmune thrombocytopenic purpura (ITP) in adults is unknown. We present the results of a prospective study in a population-based cohort of newly presenting adults (> or = 16 years) with ITP and platelet count of < 50 x 109/l, which took place between 1 January 1993 and 31 December 1999 in the former Northern Health Region in the UK (population 3.08 million...

BACKGROUND Reliable estimation of future trends in life expectancy and the burden of disability is crucial for ageing societies. Previous forecasts have not considered the potential impact of trends in disease incidence. The present prediction model combines population trends in cardiovascular disease, dementia, disability, and mortality to forecast trends in life expectancy and the burden of d...

1920x1200 abstract: background: down syndrome is the most common chromosomal abnormality due to 21 trisomy that usually is accompany with congenital heart diseases. about fifty present of children with down syndrome have heart defects. this study was designed for the aim of abundance percents of septal heart defects in children with down syndrome at imam reza and imam ali hospitals in kermansha...