INTRODUCTION The increasing burden of dengue fever (DF) in the Americas, and the current epidemic in previously unaffected countries, generate major costs for national healthcare systems. There is a need to quantify the average cost per DF case. In Mexico, few data are available on costs, despite DF being endemic in some areas. Extrapolations from studies in other countries may prove unreliable...

Background To date, research on priority-setting for new vaccines has not adequately explored the influence of the global, national and sub-national levels of decision-making or contextual issues such as political pressure and stakeholder influence and power. Using Kapiriri and Martin’s conceptual framework, this paper evaluates priority setting for new vaccines in Uganda at national and sub-na...

micro-leakage, one of the major reasons for recurrent decays, may lead to uncontrollable flow of liquids, pulp inflammation and peri-apical pathology. the purpose of this in vitro study was to evaluate micro-leakage of pit and fissure sealants after using three different pit and fissure preparation techniques: 1) acid etching, 2) fissure enameloplasty and acid etching, and 3) air abrasion and a...

Disease control efforts directed at human immunodeficiency virus are predicated on the need to reduce personal risk behaviors; that approach may not adequately reflect the complicated interplay between personal behaviors and the social setting in which they occur. Efforts to date, including the application of population ecology, the development of the core group hypothesis, and the use of compa...

Article history: Received 9 November 2012 Received in revised form 27 June 2013 Accepted 28 August 2013 Available online 27 November 2013 This study focuses on the appropriation process of two public computing infrastructures in the City of Oulu, Finland, a municipalWiFi network and large interactive displays. We analyze the adoption of these technologies in public urban places with a conceptua...

This report describes the development of an evidence-based guideline for external hemorrhage control in the prehospital setting. This project included a systematic review of the literature regarding the use of tourniquets and hemostatic agents for management of life-threatening extremity and junctional hemorrhage. Using the GRADE methodology to define the key clinical questions, an expert panel...

STUDY OBJECTIVE To assess the effect of computers and computer-based clinical decision support systems on the management of hypertension. DESIGN Systematic review of randomised controlled trials. SETTING Ambulatory hypertension clinics, community-based health centres, and general practices. PARTICIPANTS 11,962 patients enrolled in seven trials retrieved from a systematic search (electroni...

Title: Exploring the factors affecting the implementation of tobacco and substance use interventions within a secondary school setting: a systematic review Authors: Gillian Waller ([email protected]) Tracy Finch ([email protected]) Emma Giles ([email protected]) Dorothy Newbury-Birch ([email protected]) Version: 1 Date: 01 Jul 2017 Author’s response to reviews: Authors (GW, TF, ...

OBJECTIVE To identify case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), and explore how the validity of case definitions can be evaluated in the absence of a reference standard. DESIGN Systematic review. SETTING International. PARTICIPANTS A literature search, updated as of November 2013, led to the identification of 20 case definitions and inclusion of 38 ...