Objective(s): HTLV-I and HIV virus quantification is an important marker for assessment of virus activities. Since there is a direct relationship between the number of virus and disease progression, HTLV- I and HIV co-infection might have an influence on the development of viral associated diseases, thus, viral replication of these viruses and co-infection were evaluated.   Materials and...

Background and Aims: Human T-lymphotropic virus (HTLV) is a human retrovirus which has been known to cause adult T-cell leukemia/lymphoma and some other inflammatory disorders. Patients with hereditary bleeding diseases are at high risk for these viruses. In this study, we evaluated serological HTLV-I/II infection among these patients in west Azerbaijan of Iran. Material and Methods: We stud...

Background: The northeast of Iran is one the endemic regions human T-cell lymphotropic virus type-1 (HTLV-1). This study aimed to evaluate relationship between nasopharyngeal carcinoma and HTLV-1 infection in Iran, an area for HTLV-1. Methods: In this case-control study, paraffin-embedded tissue samples patients with definitive were evaluated presence genome by polymerase chain reaction retrosp...

OBJECTIVES This paper reports for the first time three cases of infection by HTLV-I via organ transplantation; all the organs coming from the same asymptomatic infected donor. The need is considered for the implementation of compulsory screenings for HTLV antibodies on organ donors and on blood banks. METHODS The determination of antibodies for HTLV-I/II on samples of serum and cerebral spina...

Background: Retroviruses of human T-lymphotropic viruses (HTLV-1 and HTLV-2) have been demonstrated to be endemic in the north-eastern region of Iran. This study aims to determine HTLV-1 and HTLV-2 prevalence among healthy individuals in Neyshabur City during 2010-2014. Methods: A total of 8054 blood samples were collected from healthy participants in Neyshabur, North-Eastern Iran. The blood sa...

Adutt T-cell leukemia (ATL) is a human T-cell leukemia virus type I (HTLV-l)-infected lymphoproliferative disorder that shows a characteristic nodular infiltration into various tissues, hypercalcemia, and subsequent rapid increase of peripheral ATL cell number. ATL cells and HTLV-l-infected T-cell lines also make cluster formation rapidly after the nonstimulative culture. However, the mechanism...

The capacity of the peripheral blood lymphocytes (PBL) to generate an antibody response in vitro to T cell-dependent antigen ovalbumin was studied in 12 severe hemophilia patients who were otherwise in good health. PBL from four of 1 2 patients were not capable of generating such a response after stimulation in vitro, whereas all controls were normal. This negative plaque-forming cell (PFC) res...

Abstract In contemporary history, several forms of civil society organizations have stood out in the struggle to expand rights. Non-governmental dedicate themselves extending rights group for which they were created. This study shows work HTLVida NGO introduce HTLV governmental agenda Bahia State, Brazil, and extend this population. is a retrovirus affecting T lymphocytes can cause neurological...

Objectives: This paper reports for the first time three cases of infection by HTLV-I via organ transplantation; all the organs coming from the same asymptomatic infected donor. The need is considered for the implementation of compulsory screenings for HTLV antibodies on organ donors and on blood banks. Methods: The determination of antibodies for HTLV-I/II on samples of serum and cerebral spina...