BACKGROUND Transfusing blood products may induce inflammatory reactions within the vascular compartment potentially leading to a systemic inflammatory response. Experiments were designed to assess the inflammatory potential of different blood products in an endothelial cell-based in vitro model and to compare baseline levels of potentially activating substances in transfusion products. METHOD...

Millions of blood products are transfused every year; many lives are thus directly concerned by transfusion. The three main labile blood products used in transfusion are erythrocyte concentrates, platelet concentrates and fresh frozen plasma. Each of these products has to be stored according to its particular components. However, during storage, modifications or degradation of those components ...

INTRODUCTION Advances in screening for infections improve the safety of donated blood. Transfusion-related bacterial sepsis, although not established in Zimbabwe, stills makes bacterial contamination of blood clinically relevant. METHODOLOGY This cross-sectional study was conducted in Harare. Bacteriological and antibiotic susceptibility testing were done using standard methods. RESULTS Of ...

objective to investigate association between nosocomial infection, blood products transfusion and microorganisms responsible in patients who hospitalized at icu (intensive care unit). patients and methods in this prospective study, 217 patients who were admitted to the icu of taleghani hospital between august 2010 and august 2011 were included. nosocomial infections were defined using the conta...