BACKGROUND Atypical squamous cell cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and low-grade intraepithelial lesion cannot exclude high-grade squamous intraepithelial lesion (LSIL-H) are ambiguous diagnostic entities for the prediction of high-grade cervical lesion. Objective and reproducible tests for predicting high-grade cervical lesions are needed to reduce unnecessary ...

GNSS augmentation systems that provide integrity guarantees to users typically assume that all GNSS satellites have the same failure probability. The assumed failure probability is conservative such that variations among satellites in a given GNSS constellation are not expected to violate this assumption. A study of unscheduled GPS satellite outages from 1999 to present shows that, as expected,...

Introduction: Detection of malignant cells in the peritoneal cavity indicates the extension of cancer cells. The aim of this study is to evaluate the incidence rate of positive cytology in colorectal cancer and its relationship with the local progress of the tumor.  Methods: In a 2-year prospective study in Mashhad and Iran Universities of Medical Sciences, peritoneal lavage was performed on...

Solitary fibrous tumors (SFTs) have been shown to harbor the characteristic NAB2-STAT6 gene fusion. Some recent studies have suggested that STAT6 is a useful marker for the diagnosis of SFTs. The aim of this study was to evaluate the diagnostic value of monoclonal anti-STAT6 in the distinction of SFTs from histologic mimics. The expression of STAT6 was evaluated in tissue microarrays and in who...

Formin FH2 domains associate processively with actin-filament barbed ends and modify their rate of growth. We modeled how the elongation rate depends on the concentrations of profilin and actin for four different formins. We assume that (1) FH2 domains are in rapid equilibrium among conformations that block or allow actin addition and that (2) profilin-actin is transferred rapidly to the barbed...