In an in vitro assay employing reconstituted nuclei, importin 7 (IPO7) has been implicated in nuclear translocation of human immunodeficiency virus type 1 (HIV-1) cDNA. Using RNA interference technology, we inhibited expression of IPO7 by 80 to 95% in primary macrophages and in HeLa cells and monitored their ability to support HIV-1 and simian immunodeficiency virus (SIV) cDNA synthesis, nuclea...

background: chronic inflammation and dys-regulation of the immune system mechanisms are now well established as primary triggers of gastric cancer and peptic ulcer disease. galectin-9 (gal-9) is a member of the galectin family and known as an inducer of cell aggregation, adhesion and apoptosis. gal-9 interaction with its main ligand t-cell immunoglobulin and mucin domain protein-3 (tim-3) leads...

Let us briefly describe a pedagogical example from [15] and a real-life example. Our pedagogical example is a triangle. A triangle is described by its angles A,B, C and side lengths a, b, c, and we know the following relations between them: A+ B+C = π (the sum of the angles is 180, or π radians), a2+b2−2ab cosC = c and similar expressions for a and b (cosine theorem), and a/ sin A = b/ sin B = ...

Introduction The Creativity and Cognition Research Studios (C&CRS) were established for the purposes of developing new art and technology projects and to conduct research into the creative process. In the COSTART Project 1998-2003 an innovative approach to the study of technology-based art founded on practice-led research methods has been developed. The work centers on the practice of art makin...

When dysarthrics, individuals with speaking disabilities, try to communicate using speech, they often have no choice but to use speech synthesizers which require them to type word symbols or sound symbols. Input by this method often makes realtime communication troublesome and dysarthric users struggle to have smooth flowing conversations. In this study, we are developing a novel speech synthes...

While texture synthesis has been well-studied in recent years, real-time techniques remain elusive. To help facilitate real-time texture synthesis, we divide the task of texture synthesis into two phases: a relatively slow analysis phase, and a real-time synthesis phase. Any particular texture need only be analyzed once, and then an unlimited amount of texture may be synthesized in real-time. O...

This paper describes an approach to reconstruction of the Polish diacritic signs, needed e.g. in a speech synthesis system. Some telecommunication services (for example SMS transmission in GSM) remove diacritics from the text. Without them the text is usually still understandable to a reader, but if a TTS system reads it, the speech becomes heavily distorted. In this paper we propose to use neu...

This paper discusses some ideas for the requirements and methods of conversational speech synthesis, based on experience gained from the collection and analysis of a very large corpus of conversational speech in a variety of real-life everyday contexts. It shows that because variation in voice quality plays a significant part in the transmission of interpersonal and affect-related social inform...

Abstract— The purpose of this paper is to give a compact summary of recent results based on the concept of a regular positive-real function. We will list an efficient set of networks which is capable of realising all biquadratics which are realisable by 5-element networks or 6-element networks of seriesparallel type. The structures are simpler than the full BottDuffin synthesis, though there ar...