نتایج جستجو برای: cytotoxic effects

تعداد نتایج: 1586380  

Background: Due to increased cancer chemotherapy resistance, the use of natural compounds in cancer treatment has been considered in recent years. Inula-Oculus-Christi, is one of the high importance plants in the field of traditional medicine. It has been shown that extract of this plant has cytotoxic effects on breast cancer cells. Objective: Therefore, the aim of this study was to evaluate t...

Journal: :iranian journal of pharmaceutical research 0
sahar behzad school of pharmacy, shahid beheshti university of medical sciences, tehran, iran atefeh pirani traditional medicine and materia medica research center, shahid beheshti university of medical sciences, tehran, iran. mahmoud mosaddegh traditional medicine and materia medica research center, shahid beheshti university of medical sciences, tehran, iran

medicinal plants have been investigated for possible anti-cancer effects. the aim of the present study was to examine the cytotoxic activity of several medicinal plants on different tumor cell lines. 11 selected plant species which have been used in folkloric prescriptions were collected from different sites of hamedan district of iran. the methanolic extracts of the plants were prepared and th...

Alireza Zamani, Fatemeh Zeraati, Kaivan Razzaghi Mohammad Taghi Goodarzi, Seyed Mansour Malakouti Hashjin

Background: One of the major paths for drug development is the study of bioactivities of natural products. Therefore, the aim of this study was to compare the cytotoxic effects of aqueous extract of whole Cuscuta chinensis Lam., which is a traditional medicinal herb commonly used in Iran and other oriental countries, on the human caucasian acute lymphoblastic leukemia (CCRF-CEM) and another hum...

حسینی, محمد, سکوتی, زهرا, شیروی, عبدالحسین, مشرفی, امیرحسین, چنگیزی, رضا,

Background and purpose: Cancer is one of the leading causes of mortality worldwide. Acute promyelocytic leukemia, which is the most common type of blood cancer in adults, is the most prevalent type of acute leukemia. This type of cancer is characterized by uncontrolled proliferation, inhibited differentiation of immature myloied progenitors (promyelocytes), and accumulation of abnormal promye...

Background: Various studies have shown that plant extracts may have cytotoxic effects on cancer cells. The aim of this study was to determine the effects of Rhamnus frangula miller leaf on viability of breast cancer cells in cell culture. Methods: In this laboratory experimental study breast cancer cell line (MCF-7) was used. MCF cells were cultured in RPMI 1640 culture medium containing 10% f...

Journal: :iranian journal of pharmaceutical research 0
firouz faedmaleki faculty of veterinary medicine, islamic azad university - science and research branch, tehran, iran farshad h shirazi pharmaceutical sciences research center, shahid beheshti university of medical sciences, tehran, iran amir salarian deptartment of toxico-pharmacology, faculty of pharmacy, shahid beheshti medical university, tehran, iran hamidreza ahmadi ashtiani department of biochemistry and nutrition, zanjan university of medical sciences, iran islamic azad university, pharmaceutical seines branch, tehran, iran. hossein rastegar department of basic science, science and research branch, islamic azad university, tehran, iran.

nano-silver (agnp) has biological properties which are significant for consumer products, food technology, textiles and medical applications (e.g. wound care products, implantable medical devices, in diagnosis, drug delivery, and imaging). for their antibacterial activity, silver nanoparticles are largely used in various commercially available products. thus, the use of nano-silver is becoming ...

Journal: :archives of breast cancer 0
behzad mohaddesi department of pharmaceutical sciences, saurashtra university, rajkot, gujarat, india ashvin dudhrejiya b.k. mody government pharmacy college, rajkot, gujarat, india navin r. sheth department of pharmaceutical sciences, saurashtra university, rajkot, gujarat, india

background: in the modern lifestyle, the increase in cancer and related chronic disorders is a major public health problem. in spite of different methods used for the treatment of these conditions, natural medicines have high demands due to their significant effects as immune enhancement and therapeutic agents and fewer side effects in comparison with other treatment methods. hence, this study ...

Farideh-Sadat Makki Mahdi Mojarrab, Nafiseh-Sadat Alamolhodaei Seyed Ahmad Emami, Zahra Tayarani-Najaran,

Objective(s): Artemisia is a genus of herbs and small shrubs forms an important part of natural vegetation in Iran. It has been reported that several Artemisia species possess anti-proliferative effects. Considering the value of this genus in anti-cancer researches we have chosen Artemisia biennis for cytotoxic and mechanistic studies. Materials and Methods:In this study we have investigated th...

Sulfonamides are the first effective chemotherapeutic agents used for several years to cure or prevent systemic bacterial infections. In addition, this agents showed anti-carbonic anhydrase and cause cell cycle perturbation in the G1 phase, disruption of microtubule assembly, suppression of the transcription activator Nf-Y, angiogenesis and matrix metalloproteinase (MMP). In recent years, novel...

A Salarytabar, B Farahanikia, A Hadjiakhoondi , F Hadjiakhoondi , M Khanavi , SN Ostad ,

Background: Numerous molecules in Papaveraceae family display interesting cytotoxic activities against tumor cell lines in vitro and hints of anticancer activities in vivo have been reported in a few cases. Objective: Numerous molecules in this family display interesting cytotoxic activities against tumor cell lines in vitro and hints of anticancer activities in vivo have been reported in a fe...

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