The effects of systemic insulin administration at different concentrations on the testicular tissue diabetic adult rats, induced by streptozotocin, are evaluated morphological analysis spermatogenic process. Twenty-four male rats were divided into 1) Control Group: they received citrate buffer, intraperitoneal injection; 2) Diabetic injection streptozotocin (60 mg. kg-1 body weight); 3) Insulin...

background: insulin receptor substrate (irs) type 1 is a main substrate for the insulin receptor, controls insulin signaling in skeletal muscle, adipose tissue, and the vascular, so it is an important candidate gene for insulin resistance (ir). we aimed to compare the  effects of the dietary approaches to stop hypertension (dash) and usual dietary advices (uda) on irs1 gene expression in women ...

Oral CDCA and UDCA have different effects on gut pancreatic hormone secretion. A single dose of increased fasting secretion the hormones GLP-1 OXM with an accompanying increase in insulin also reduced postprandial GIP secretion, which was associated insulin. In contrast, did not change or postprandially. could be beneficial to patients obesity diabetes.

Objective(s): Both caloric restriction (CR) and resveratrol (RSV) have been shown to improve learning and memory, but their potential effects in juvenile animals were unknown. Here, we evaluated the effects of RSV and CR on learning and memory function in juvenile mice and investigated potential molecular mechanisms. Methods: Six-week-old C57BL/6J mice were assigned to one of three different d...

background : insulin-like growth factor-1 can act in both an autocrine and paracrine manner to promote normal growth and malignant cellular proliferation. the importance of this factor as a major regulatory peptide has been established for cells, in vitro and in vivo. however, the role of serum insulin-like growth factor-1 levels in the etiology of benign prostatic hyperplasia and prostate canc...

background: the effect of high‑legume hypocaloric diet on metabolic features in women is unclear. this study provided an opportunity to find effects of high‑legume diet on metabolic features in women who consumed high legumes at pre‑study period. methods: in this randomized controlled trial after 2 weeks of a run‑in period on an isocaloric diet, 42 premenopausal women with central obesity were ...

Objective(s): Visfatin and vaspin are secreted by adipose tissue and play key roles in glucose homeostasis and subsequently are potential targets for diabetes treatment. Resveratrol (RVS) corrects insulin secretion and improves insulin sensitivity. We investigated the RVS effects on serum antioxidants, insulin and glucose levels, also visfatin and vaspin genes expression in adipose tissue of st...