In 1988 Sudoh and colleagues described a novel natriuretic peptide in porcine brain -brain natriuretic peptide(Sudoh et al. 1988). In fact, the peptide is most abundant in the heart and thus it is now commonly termed B-type natriuretic peptide (BNP). Myocyte pressure and/or stretch results in the release of BNP, and BNP levels are easily quantified by several commercially available assays. Data...

Wave Reflection in Systolic Hypertension: Smaller Stature, Shorter Aorta: Higher Pulse Pressure? To the Editor: In a recent issue of Hypertension, Mitchell et al1 suggested that, among patients with systolic hypertension, reduced aortic diameter and increased wall stiffness, rather than premature wave reflection, are primarily responsible for increasing pulse pressure (PP). We share the concern...

Capturing and measuring qualities of the built environment is a fundamental aspect of planning. Planners need to develop a vivid picture of the physical and social environments people inhabit in order to understand what impacts their plans and actions may have. Measures can indicate the built environment’s qualities and represent them in a way that is useful for planning to address particular i...

Sir, In a recent article discussing the cognitive roots of schizophrenic communicative behaviour, Mitchell and Crow (2005) emphasized the importance of full access to right hemisphere language functions to ensure successful social communication. Based on the literature describing communicative deficits among right-hemisphere-damaged (RHD) patients, as well as on the literature reporting functio...

Researchers who study the neuronal basis of cognition face a paradox. If they extract the brain, its cognitive functions cannot be assessed. On the other hand, the brain's microcircuits are difficult to study in the intact animal. In this issue of Neuron, Mitchell et al. make use of a promising approach based on waveform analysis to reveal new details about neuronal interactions during visual a...

1) Co-author Mitchell James Schwaber is listed with credentials MD, MPH. The correct credentials are MD, MSc. 2) Reference 64 contains an error in the author list. Author “Araj F” should be “Araj GF.” 3) References 114 and 115 contain errors in the author lists. The phrase “et al.” should appear after the 3 listed author in both reference entries. 4) Reference 124 contains an error in the autho...