Several studies suggest that the biological responses induced by manufactured nanoparticles (MNPs) may be linked to their accumulation within cells. However, MNP internalisation has not yet been sufficiently characterised. Therefore, the aim of this study was to compare the intracellular uptake of three different MNPs: two made of carbon black (CB) and one made of titanium dioxide (TiO(2)), in ...

     Extracts derived from Viscum album have been shown to kill cancer cells in vitro. Some studies have noted that different species of this plant collected from around the world displayed cytotoxic effects in different extents. In the present study, we evaluated the effects of Iranian mistletoe extracts on five cancer cell lines. Plants growing on hornbeam tree (Carpinus...

Whipple's disease is considered a rare chronic disease with a broad spectrum of clinical manifestations. Several antibiotics have been used for the treatment of this disease, and the current reference treatment was determined empirically on the basis of only a few clinical observations. Patients should be treated for months, and many relapse after antibiotic withdrawal. We report here the first...

This study aimed to evaluate the chemical composition of the essential oils from three genotypes of Lippia gracilis Schauer (Verbenaceae) and investigate the cytotoxic activities of these oils. Essential oils were extracted from the leaves using a Clevenger-type apparatus, and chemical analysis was performed using a gas chromatograph coupled to a mass spectrometer and flame ionization detector....

A transmissible agent, the IM virus, antigenically related to the Japanese subacute myelo-optico-neuropathy virus, has been isolated from several human cerebrospinal fluids obtained from American patients with multiple sclerosis and other chronic diseases of the central nervous system. The isolates were propagated in human diploid fibroblast (MRC5) cells, and virus was released into the culture...

The objective of this study was to the synergistic antitumor effect lipophilic bismuth nanoparticles (BisBAL NPs) with antibiotic solution Neo-Poly gramicidin on human cervical tumor cells. BisBAL NPs and cancer cell line (HeLa) determined by MTT viability assay fluorescence microscopy. After a 24-h exposure 0.1× HeLa growth decreased 94%. Fluorescence microscopy confirmed death higher among tr...

background: the aim of this study was to clarify the mechanism by which lactobacilli exert their cytotoxic effects on cervical cancer cells. in addition, we aimed to evaluate the effect of lactobacilli on the expression of human papilloma virus (hpv) oncogenes. materials and methods: in this experimental study, using quantitative real-time polymerase chain reaction (pcr), we analyzed the expres...

Regarding the high prevalence of cancer, research on medicinal plants have been increased due to their availability, cost, and the presence of anticancer compounds. Rorippa nasturtium aquaticum, also called watercress, is a plant from the Brassicaceae family which has large amounts of antioxidants. The present study aimed to examine the antioxidant properties and the phenolic, flavonoid, and an...