Wheat is a crop with spring and winter types and wide adaptability to different climate conditions. The wide adaptability of wheat is mainly controlled by three groups of genetic factors and among them vernalization (VRN) genes play pivotal role in determining spring and winter types. In this study, 395 Iranian wheat landraces were characterized with specific primer pairs designed based on VRN-...

Inorganic arsenicals are worldwide environmental contaminants that affect molecular characteristics in biological systems and lead to genomic and epigenomic instability as well as epithelial mesenchymal transition (EMT). In this study, we aimed to investigate whether low levels of sodium arsenite (iAsIII) can influence EMT and genomic instability through microsatellite analysis. We have also de...

the p21 belongs to the cip/kip family of cdk inhibitors involved in cell cycle arrest at specific stages of the cell cycle progression. dna methylation is the best studied epigenetic mark that have been evidently associated to chromatin condensation, and repression of gene transcription. the cpg island hypermethylation in promoter region of certain genes occurs in cancer cells and affects tumor...

background: poor ovarian response phenomenon has been observed in some of the in vitro fertilization-embryo transfer patients. some investigations found that follicle stimulating hormone receptor (fshr) gene plays a role in the process, but no direct evidence shows the correlation between genotypes of fshr and ovarian response. objective: exploring the molecular mechanism behind the mutation of...

objective: development of high producing mammalian cell lines is a major bottleneck in manufacturing of recombinant therapeutic proteins. this study examines the effect of using the matrix attachment region from the human interferon beta gene in combination with promoter activation strategy with e1a 13s protein on human tissue plasminogen activator (t-pa) expression in chinese hamster ovary (ch...

This research aims to know, analyse, and explain: The extent of the relationship between education level training on competency participants graduates. Partial influence competence graduates participants. Simultaneous Data collection techniques using questionnaire literature. population in this is a participant who graduated at PT Satria Tamtama Rahayu has been placed industrial company with sa...

Background: IL-10 is an anti-inflammatory cytokine which is involved in tumorigenesis. Over production of IL-10 and elevated number of IL-10 generating mononuclear cells in breast tumor tissue has already been shown. Objective: To determine the association of IL-10 promoter polymorphisms with increased risk of breast cancer and its association with breast cancer prognostic factors. Methods: Per...