background: polycystic ovarian syndrome (pcos) is one of the most common endocrine disorders which cause anovulatory infertility and hyperandrogenism in young women. the common feature in pcos women is increased ovarian androgen secretion which can effect on the prevalence of miscarriage rate. objective: the aim of this study was to investigate the effect of pcos patient's serum on in vitro dev...

BACKGROUND The significance of polycystic ovarian morphology and its relation to polycystic ovary syndrome (PCOS) is unclear, but probably it is associated with higher androgen and insulin levels and lower sex hormone binding globulin (SHBG) in absence of identifiable differences in gonadotropin dynamics. The aim of this study was to evaluate ovarian morphology in patients affected by PCOS with...

This study aimed to detect the levels of matrix metalloproteinases (MMP)-2 and -9, using enzyme-linked immunosorbent assays, in the follicular fluid of 35 patients with polycystic ovaries, compare them with the levels found in 35 normally ovulating women enrolled in their first in vitro fertilization (IVF) cycle and then correlate them with pregnancy rates in these two groups. Levels of MMP-9 w...

Primary cilia are nonmotile, microtubule-based, antenna-like organelles projecting from the apical surface of most mammalian cells. Elegant studies have established the importance of ciliary structure and function in signal transduction and the sensory roles of cilia in maintaining healthy cellular state. In particular, dysfunctional cilia have been implicated in a large number of diseases main...

In the present study was performed to evaluate the follicular growth and hormonal changes after ovarian artery ligation in rats. Fifty six virgin 90-day–old female rats were used. The rats were chosen from 100 female rats by a vaginal smear, which showed that they were synchronized in estrous phase of the menstrual cycle. Animals were kept in seven cages (n=8 in each) at a temperature of 22 ± 2...

Polycystic ovarian syndrome (PCOS) is sometimes called Stein-Leventhal Syndrome after the two doctors who first described it in 1935. 1 It is the most common ovarian disorder with typical features of obesity, anovulation, hyperandrogenism, hirsutism and infertility. The accepted nomenclature for the syndrome is PCOS, despite the fact that polycystic ovaries are non-specific findings and can occ...

OBJECTIVE To evaluate the influence of ovarian follicular dominance on the outcome of oocyte in-vitro maturation. METHODS This retrospective cohort study included 21 patients with polycystic ovaries or polycystic ovary syndrome (Rotterdam criteria, 2004) subjected to 24 invitro maturation (IVM) cycles between October 2015 and January 2017. Patients undergoing IVM received minimal gonadotropin...