BACKGROUND Pulmonary tuberculosis is occasionally confused with invasive pulmonary aspergillosis (IPA) in transplant recipients, since clinical suspicion and early diagnosis of pulmonary tuberculosis and IPA rely heavily on imaging modes such as computed tomography (CT). We therefore investigated IPA-mimicking tuberculosis in transplant recipients. METHODS All adult transplant recipients who ...

OBJECTIVE To understand the current status and trends of tuberculosis mortality rates in China. METHODS In 2010, 161 National Disease Surveillance Points representing all 31 mainland provinces, municipalities, and autonomous regions of China collected tuberculosis mortality surveillance data, including age, sex, region, and type of tuberculosis (all, pulmonary, and extra-pulmonary). The morta...

It is well known that the activation of cell mediated immunity has an important role in the pathogenesis of pulmonary tuberculosis and the production of the protective immunity against Mycobacterium tuberculosis. During the activation of T-cell by Interleukin-1 released from the macrophage, not only Interleukin-2 but also the soluble Interleukin-2 receptor (sIL-2R) molecule is released into the...

Vitamin D deficiency and vitamin D receptor (VDR) gene abnormalities confer susceptibility to tuberculosis. Toll-like receptors (TLRs), such asTLR-2, are also important mediators of inflammatory response against Mycobacterium tuberculosis. We evaluated serum vitamin D, and VDR and TLR-2 gene polymorphisms in patients with spinal tuberculosis.This study comprised of 3 groups: spinal tuberculosis...

Mannose receptor is a member of the C-type lectin receptor family involved in pathogen molecular-pattern recognition, and plays a critical role in shaping host immune response. Single nucleotide polymorphisms (SNPs) in the MRC1 gene may affect expression levels and differences in the structure and function of proteins in different individuals, thereby affecting individual susceptibility to pulm...

background: the diagnosis of pulmonary tuberculosis (ptb) is complicated and time-consuming currently. there was association of ptb with serum tumor markers. in this study we aimed to evaluate the predictive role of serum ca125, ca199 and cea as diagnostic tools for ptb. methods: this study was designed as a case-control study with 565 subjects who visited the yijishan hospital from jun to dec ...

introduction: pulmonary tuberculosis is major problem worldwide and it is estimated one third the world population are already infected and each year 9 million people develop full blown tuberculosis of these 3 million die of the disease, annually. delay in diagnosis and treatment are major problems that play a significant role in all aspect of the disease from patient treatment to transmission ...

A 61-year-old man was admitted a confirmed COVID-19 with comorbid pulmonary tuberculosis and type 2 diabetes mellitus. The patient given favipiravir therapy, category 1 of antituberculosis drug, insulin therapy. responded well to therapy improved clinical laboratory indicators.
 Key words: COVID-19, tuberculosis, mellitus

PURPOSE Many medical centers routinely culture bronchoscopy samples for Mycobacterium tuberculosis, even when tuberculosis is not strongly suspected. The value of this practice, however, is controversial. We evaluated the role of that procedure in the diagnosis of pulmonary tuberculosis in an intermediate tuberculosis-burden country. PATIENTS AND METHODS A prospective, observational study was...