Background & Aims: SLC26A4 gene mutations are the second identifiable genetic cause of autosomal recessive nonsyndromic hearing loss (ARNSHL) after GJB2 mutations and are currently investigated in molecular diagnosis.In databases, several potential STR markers related to this region have been introduced. In this investigation, the characteristics and informativeness of D7S2425 CA repeat STR mar...

The need to determine the distribution of a given cellular or molecular marker within the brain is common to a wide range of neuroscience investigations. Localization is an essential parameter both for the interpretation of findings in an anatomical and functional context, as well as for comparing findings across specimens. Knowledge of temporal and spatial gene expression patterns in the brain...

Several DNA molecular markers are now available for use in surveillance and investigation of foodborne outbreaks that were previously difficult to detect. The results from several sources of literature indicate substantially different degrees of sensitivities between conventional detection methods and molecular-based methods. The new technology is noted for increased sensitivity over the tradit...

Endogenous non-coding small RNAs usually consist of 20–24 nucleotides, are found ubiquitously throughout the genome and play important regulatory roles in most eucaryotes. In this study, a new kind of PCR-based marker approach using multi-mapped small RNA sequences, called inter small RNA polymorphism (iSNAP), was developed. iSNAP primers were designed based on multi-mapped small RNA and its tw...

Trichoderma “viride” TNAU is the most widely used biofungicide in India with more than 250 registered commercial formulations being available. We have studied the phylogenetic position of this strain using a molecular marker and determined that this commercial strain is, in fact, a strain of Trichoderma asperelloides, and not T. viride. The implications of these findings on the registration and...