The heart is a major consumer of energy and is able to utilise a wide range of substrates including lipids. Nonesterified fatty acids (NEFA) were thought to be a favoured carbon source, but their quantitative contribution is limited because of their relative histotoxicity. Circulating triacylglycerols (TAGs) in the form of chylomicrons (CMs) and very-low-density lipoprotein (VLDL) are an altern...

Adaptive tree-based multicast routings for networks-on-chip (NoC) in a mesh planar router architecture are presented in this paper. Multicast packets are routed and scheduled in the NoC using a local Identity-based multiplexing technique with wormhole switching. The identity-tag attached to every flit allows different flits of different packets to be mixed in the same queue and enables to imple...

The isolated Block V repeats-in-toxin (RTX) peptide domain of adenylate cyclase (CyaA) from Bordetella pertussis reversibly folds into a β-roll secondary structure upon calcium binding. In this review, we discuss how the conformationally dynamic nature of the peptide is being engineered and employed as a switching mechanism to mediate different protein functions and protein-protein interactions...