MOTIVATION Time-course microarray experiments are designed to study biological processes in a temporal fashion. Longitudinal gene expression data arise when biological samples taken from the same subject at different time points are used to measure the gene expression levels. It has been observed that the gene expression patterns of samples of a given tumor measured at different time points are...

We propose a novel technique to boost the power of testing a high-dimensional vector H : θ = 0 against sparse alternatives where the null hypothesis is violated only by a couple of components. Existing tests based on quadratic forms such as the Wald statistic often suffer from low powers due to the accumulation of errors in estimating high-dimensional parameters. More powerful tests for sparse ...

This report investigates the influence of liver transplantation and concomitant immunosuppression on the course of progression of inflammatory bowel disease (IBD) and discusses statistical methodology appropriate for such settings. The data on 303 patients who underwent liver transplantation for primary sclerosing cholangitis (PSC) were analyzed using person-time analysis and Cox regression, wi...

background: depression is a kind of sorrow that decreases the level of juiciness. most studies have maintained that psy­chological risk factors have the most profound effect on the development of postnatal depression (pnd). we compared the postnatal depression among the women with elective caesarean and vaginal delivery.  methods: this cross- sectional study was carried out on 120 women 1-4 mon...

We introduce an analytical model, the Wald analytical long-distance dispersal (WALD) model, for estimating dispersal kernels of wind-dispersed seeds and their escape probability from the canopy. The model is based on simplifications to well-established three-dimensional Lagrangian stochastic approaches for turbulent scalar transport resulting in a two-parameter Wald (or inverse Gaussian) distri...

For the precaution against physical soil degradation in managed soils, accurate planning data about anthropogenic impacts and for policy making applicable indicators to describe the driving force and state are required. To assess the potential erosion risk, accurate information is available, but to assess the actual erosion risk it is necessary to regard current land-use and cultivation data fo...

conclusions the evaluation of the questionnaire for identifying the individuals in the risk of addiction showed that the questionnaire benefits from appropriate validity and reliability. therefore, it can be used in preventive fields and research. moreover, by illuminating interpersonal factors that are effective in drug abuse, proper strategies can be used to prevent drug addiction. results in...