Rosmarinic acid (RA) is an ester of caffeic acid and 3, 4-dihydroxyphenyllacticacid. It is commonly found in Coleus blumei, Salvia officinalis, Melissa officinalis and Rosmarinus officinalis. The biosynthesis of RA starts with precursor molecules L-phenylalanine and L-tyrosine. Simulation of RA biosynthetic pathway was done using Gepasi Software, includes the reaction kinetics of each step of t...

The end of monkey research?” ask Melissa Suran and Howard Wolinsky (2009) against a background of growing concern over the use of primates in research. Indeed, the one factor that might have the biggest impact on primate research in Europe is the revision of Directive 86/609, which will greatly affect the work of many scientists. It is therefore in the interest of all researchers to get an unbi...

This study aimed to determine the effects of plant species on biological parameters Tetranychus urticae Koch and time mite infestation physiology in Ocimum basilicum L., Melissa officinalis L. Salvia Mite induced various levels oxidative stress depending duration infestation. Host plants affected T. life table parameters. The low level susceptibility was characteristic S. officinalis, which app...

We investigated the antimutagenic activities and chemical compositionsof essential oil (EO) from Melissa officinalis, Lavandula angustifolia Origanum onites plants belonging to Lamiaceae family. The compositions of were determined by GC/MS analysis Ames assay was used in activity analysis. Citral, linalool, thymol terpinenes major components EOs M. L. O. onites. In assay, it that EO officinalis...

Purpose: The aim of this research is to see how Melissa officinalis L. affects the death pathways MCF-7 breast cancer cells in vitro.
 Materials and Methods: In order determine cytotoxic activity IC50 value 70% methanolic extract prepared from aerial parts officinalis, on cell line; was applied at different concentrations times MTT analysis performed. Apoptotic effects determined dose were...

We have tested acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of nineteen essential oils obtained from cultivated plants, namely one from Anethum graveolens L. (organic fertilizer), two from Foeniculum vulgare Mill. collected at fully-mature and flowering stages (organic fertilizer), two from Melissa officinalis L. (cultivated using organic and chemical ferti...

Kombucha is a fermented tea beverage which is traditionally prepared by fermenting sweetened black or green tea (Camellia sinensis L.) with symbiotic consortium of bacteria and yeasts (SCOBY). In this study, lemon balm (Melissa officinalis L.) was used as the only nitrogen source for kombucha fermentation. During the seven-day fermentation process, pH value, titratable acidity (TA), total pheno...

Introduction: Melissa officinalis is usually used as antispasmodic, antiaxiety and antibacterial agent. However, its toxicity has not been evaluated, yet. In this study biochemical, liver and renal toxicities of Melissa officinals hydroalcoholic extract were evaluated in balb/C mice. Methods: In an experimental study, 21 balb/C male mice were randomly designated to three equal groups. Group I w...