The smell of marijuana (Cannabis sativa L.) is of interest to users, growers, plant breeders, law enforcement and, increasingly, to state-licensed retail businesses. The numerous varieties and strains of Cannabis produce strikingly different scents but to date there have been few, if any, attempts to quantify these olfactory profiles directly. Using standard sensory evaluation techniques with u...

Background: Cannabidiol (CBD) is a non-psychoactive substance of Cannabis sativa effective in refractory epilepsy due to Dravet syndrome, Lennox-Gastaut syndrome and Tuberous Sclerosis Complex, with few studies other etiologies. There are that show benefit the mutual use clobazam CBD.

Naturally occurring cannabinoids (phytocannabinoids) are biosynthetically related terpenophenolic compounds uniquely produced by the highly variable plant, Cannabis sativa L. Natural and synthetic cannabinoids have been extensively studied since the discovery that the psychotropic effects of cannabis are mainly due to Delta(9)-THC. However, cannabinoids exert pharmacological actions on other bi...

Cannabis sativa (Cannabis) is one of the world’s most well-known, yet maligned plant species. However, significant recent research starting to unveil potential produce secondary compounds that may offer a suite medical benefits, elevating this unique species from its illicit narcotic status into genuine biopharmaceutical. This review summarises lengthy history and details molecular pathways und...

Recently, an increasing number of pharmacists had to supply medicinal products based on Cannabis sativa L. (Cannabaceae), prescribed by physicians to individual patients. Cannabis olive oil preparation is the first choice as a concentrated extract of cannabinoids, even though standardized operative conditions for obtaining it are still not available. In this work, the impact of temperature and ...

Introduction In the United States, marijuana (Cannabis sativa, possibly also Cannabis indica and Cannabis afghanica) is classified by the Drug Enforcement Administration (DEA) as a prohibited Schedule I drug ("no currently accepted medical use"). As a substitute for marijuana, the DEA approved dronabinol (Marinol®). Dronabinol is synthetic delta-9-tetrahydrocannabinol (∆-THC). It is formulated ...

The correspondence of Zias et al. (1993), related the finding of carbonized matter containing tetrahydrocannabinol (THC), the primary psychoactive component of marijuana, in the abdomen of an adolescent girl who apparently died in childbirth around 400 AD. The researchers’s hypothesis was that Cannabis was administered to women in child birth to relieve pains and increase uterine contractions b...

INSTRUCTIONS Credit can now be obtained, free for a limited time, by reading the review article in this issue and completing all activity components. Please note the instructions listed below: Review the target audience, learning objectives and all disclosures. Complete the pre-test online at http://www.annallergy.org (click on the CME heading). Follow the online instructions to read the full v...