Gastric cancer (GC) is one of the highest cancermortality diseases with a high incidence rate (Chen et al., 2013), and is the second most common cause of death from cancer in Asia (Leung et al., 2008). Surgery is the cornerstone of the management of patients with resectable GC (Van et al., 2008). For patients with advanced stage GC which are not completely resected, the palliative chemotherapy ...

Sir, The letter from Hedberg et al. (2013) is of great interest because it addresses an important question relating to the genetic aetiology of hereditary myopathy with early respiratory failure (HMERF). The original report by Lange et al. (2005) indicated that HMERF was associated with a heterozygous g.296459C4T/ p.R32450W mutation in the kinase domain of titin (TTN) (using Genebank AJ277892 a...

Bevacizumab is a recombinant humanized monoclonal antibody used for multiple solid tumors in recent years, including lung cancer (Gentzler et al., 2013; Smith et al., 2013). At present, maintenance chemotherapy is a new perspective for advanced non-small cell lung cancer (NSCLC), which refers to the maintenance therapy in a certain period of induction chemotherapy to achieve the maximum tumor r...

Drought-induced forest mortality is emerging as a widespread phenomenon with potentially large 12 implications for forest function and dynamics (Allen et al., 2010; Anderegg et al., 2012; Martínez13 Vilalta et al., 2012). Although the physiological mechanisms underlying tree mortality are still not 14 completely understood, there is agreement that they involve the storage and transport systems ...

Introduction Ischemic strokes, caused by cerebral artery stenosis or occlusion, lead to a reduction or abrupt interruption of local cerebral blood flow, resulting in anoxia in the arterial territory, secondary vascular endothelial injury, and the initiation of various pathological conditions (Jian et al., 2013; Kim et al., 2013; Wang et al., 2014). With technological advances, the clinical diag...

Understanding how the brain controls motor behavior and generates cognitive functions still remains one of the most challenging goals in science and neuroscience in particular. Toward this goal it is important to use a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology, and mathematical modeling. This strategy is most efficient when using animal mod...

Cancer is the third most common cause of death following cardiovascular disease and accident (Mohebbi et al., 2008; Moradpour and Fatemi, 2013) and gastrointestinal (GI) cancers are the most frequent cancers among males and second to females’ breast cancer in Iran (Mohebbi et al., 2011). The epidemiological characteristic of upper GI cancer has markedly changed over recent decades so that oesop...