BACKGROUND Rational health care decision-making based on outcomes and economic evidence is essential to provide the best possible care for individual patients with atopic dermatitis (AD). OBJECTIVES To describe treatment outcomes and to evaluate resource utilization and associated cost of maintenance use of tacrolimus ointment (MU) vs. standard use of tacrolimus ointment (SU) in adults with A...

BACKGROUND Traditional Chinese medicine (TCM) has a long history in the treatment of psoriasis vulgaris. We aimed to evaluate the clinical efficacy and safety of Chinese herbal Pulian ointment in treating psoriasis vulgaris of blood-heat syndrome. METHODS A multicenter, randomized, double-blind, placebo-controlled trial was conducted. Participants with psoriasis vulgaris of blood-heat syndrom...

Aciclovir is rapidly absorbed from the ophthalmic ointment through the corneal epithelium and superficial ocular tissues with the result that viral toxic concentrations are achieved in the aqueous humor. It has not been possible to detect aciclovir in the blood by existing methods after topical application of ZOVIRAX Ophthalmic Ointment, but trace quantities are detectable in the urine. These l...

A review of 783 patients with non-penetrating, superficial corneal foreign bodies (FBs), indicated that delay in rehabilitation was related to two factors: (1) the size of the abrasion following removal of the FB, larger abrasions requiring longer duration of antibiotic ointment, and (2) inadequate removal of corneal rust. Allergy to chloramphenicol 1% ointment (5.5 in 1000), commonly used in t...

Background & Aim: Onosma stenosiphon has been used as herbal medicine for healing skin cuts and rashes. However, burn healing effect of this herb has not been yet reported in pharmaceutical texts. The aim of this study was to find out the effect of herb ointment on burn healing the superficial wounds post type II burns of back and testis region in Wistar rats. Experimental: A total of...

Clobetasone butyrate is a new corticosteroid, selected for study because of its combination of good activity in the vasoconstriction test and low systemic activity in animals. Formulated as an 0.05% ointment and cream (Molivate) it was clinically effective in patients with eczema, its activity being significantly greater than that of hydrocortisone 1% or fluocortolone 0.2% (Ultradil). Under con...

A 56-year-old Japanese man hospitalized for schizophrenia and depression developed pressure ulcer on his greater trochanter due to a long-term bed rest. In spite of applying 0.003% alprostadil alfadex ointment for two months, the ulcer was not improved. Because there was some purulent discharge, we examined semi-quantitative swab bacterial culture from the ulcer and subsequently detected quadra...

to determine whether the medical treatment of anal fissure can be an effective alternative for surgery methods: retrospectively, we randomly selected 190 patients being treated for anal fissure between the years 2005-2010 in 3 equal groups: group a: patients who received medical treatment with topical nitroglycerin, group b: patient treated with topical diltiazem, and group c: patients underwen...