Natural or synthetic hydroxyapatite (HA) has been frequently used as implant materials for orthopaedic and dental applications, showing excellent bioactivity, adequate mechanical rigidity and structure, osteoconductivity and angiogenic properties, no toxicity, and absence of inflammatory or antigenic reactions. HA can be easily synthesized or extracted from natural sources, such as bovine bone....

Achieving the stability of bone tissue in field dental implants is still most urgent and completely unsolved problem implantological practice. Modern ideas about biological principles structure functioning tissues periimplant zone are one significant factors ensuring crestal tissue. The soft-tissue component that forms basis complex at implant-suprastructure interface plays a key role protectin...

background and aims. complete and predictable regeneration of tissue lost as a result of infection or trauma is the ultimate goal of periodontal therapy. various graft materials have been successfully used in the treatment of intrabony defects. the purpose of this study was to evaluate the use of a decalcified freeze-dried bone allograft (cerabone) with the autogenous bone graft as a gold stand...

This study aimed to explore and validate a new juvenile osteopenic (JO) rat model then examine the efficacy of moghat (Glossostemon bruguieri) as an alternative reversal therapy for JO. Phytochemical screening analysis showed that moghat contains 5.8% alkaloids, 1.5% flavonoids and 13.2% total phenols. Juvenile osteopenia was induced in 15 days old Sprague- Dawley female rats by feeding them fr...

Nanofiber scaffolds and bio-ceramic nanoparticles have been widely used in bone tissue engineering. The use of human induced pluripotent stem cells (hiPSCs) on this scaffold can be considered as a new approach in the differentiation of bone tissue. In the present study, a polyaniline-gelatin-polycaprolactone (PANi-GEL-PCL) composite nanoscaffold was made by electrospinning and modified superfic...

stafne bone cavities (sbcs) are uncommon well‑demarcated defects of the mandible, which often occur in the posterior portion of the jaw bone and are usually asymptomatic. furthermore, sbc is found in men aged 50–70‑year‑old. anterior mandibular variants of sbc are very rare. this article describes a case of anterior sbc in a 45‑year‑old man that resembled endodontic periapical lesions. upon his...

Silver nanoparticles (Ag NPs) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. Present study compares the tissue levels of Ag NPs in different organs of Guiana Pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the Ag NPs tissue levels. Before toxicological assessments,the...

both anorganic bovine bone (abb) and β-tricalcium phosphate (β-tcp) are used in clinical practice as bone substitute materials, but there is limited data comparing these two materials in standardized defects. the aim of this study was to histologically evaluate the effectiveness of abb and β-tcp in the healing of experimentally induced bone defects.eighteen bone defects were created on the calv...

Need for regeneration and repair of nasal tissues occurs as a consequence several pathologies affecting the nose, including, but not limited to infective diseases, traumas tumor resections. A platform tissue was set up using poly(vinyl alcohol)/gelatin sponges with 20%–30% (w/w) gelatin content be used scaffolds, their intrinsic hydrophilic, cell adhesive shape recovery properties. We propose m...

Silver nanoparticles (Ag NPs) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. Present study compares the tissue levels of Ag NPs in different organs of Guiana Pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the Ag NPs tissue levels. Before toxicological assessments,the...