نتایج جستجو برای: chr m 1
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We investigated the effect of apolipoprotein E (Apoe) on albuminuria in the males of two independent F2 intercrosses between C57BL/6J and A/J mice, using wild-type inbred strains in the first cross and B6-Apoe(-/-) animals in the second cross. In the first cross, we identified three quantitative trait loci (QTL): chromosome (Chr) 2 [LOD 3.5, peak at 70 cM, confidence interval (C.I.) 28-88 cM]; ...
Article Die Antäus-Sage in der Theologie Erde von Dietrich BonhoefferAlle Texte Bonhoeffers sind im Chr. Kaiser Verlag erschienenen Gesamtausgabe entnommen (Kurzbezeichnung: DBW). was published on December 1, 2022 the journal Antike und Abendland (volume 68, issue 1).
The potential utility of the Collaborative Cross (CC) mouse resource was evaluated to better understand complex traits related to energy balance. A primary focus was to examine if genetic diversity in emerging CC lines (pre-CC) would translate into equivalent phenotypic diversity. Second, we mapped quantitative trait loci (QTL) for 15 metabolism- and exercise-related phenotypes in this populati...
PURPOSE Patients with hypereosinophilic syndrome (HES) or chronic eosinophilic leukemia (CEL) that are refractory to standard therapies are difficult to manage and have significantly shortened life expectancy. EXPERIMENTAL DESIGN CD52 is a surface glycoprotein highly expressed on eosinophils. We treated 11 patients with advanced HES/CEL with alemtuzumab, a humanized anti-CD52 monoclonal antib...
There is inconsistent evidence for increased stress exposure among individuals at clinical high risk (CHR) for psychosis. Yet similar to patients with a diagnosed psychotic illness, the preponderance of evidence suggests that CHR individuals tend to experience stressful life events (LE) and daily hassles (DH) as more subjectively stressful than healthy individuals. The present study utilizes da...
Survivin is the first apoptosis inhibitor described to date to be expressed in G2-M in a cell cycle-dependent manner and to directly associate with mitotic spindle microtubules. To gain additional insights into this novel apoptotic checkpoint, we have now characterized the mouse survivin locus. Hybridization screening of mouse BAC libraries identified a survivin gene containing four exons and t...
In this paper, an M/M/1 queue with instantaneous Bernoulli feedback is studied in the event of server failure, the catastrophe occurs and after repair, it starts to work again. The transient response for the probability function of the system size is presented. The steady state analysis of system size probabilities and some performance measures of system are provided. Then the resu...
C57BL/6J (B6) and DBA/2J (D2) strains and two derivative populations, BXD recombinant inbred strains (BXD RIs) and B6D2F2, were used to explore genetic basis for variation in muscle weight at 500 days of age. In parallel with findings in 200-day-old mice (Lionikas A, Blizard DA, Vandenbergh DJ, Glover MG, Stout JT, Vogler GP, McClearn GE, and Larsson L. Physiol Genomics 16: 141-152, 2003), weig...
Constraint Handling Rules (CHR) is a declarative rulebased concurrent committed-choice programming language. Petri nets are a well-known formalism for modeling and analysis of concurrent processes. We aim to develop a framework to exploit Petri nets as a tool for the modeling and analysis of CHR programs. In this paper, we show that place/transition nets can easily be embedded into CHR and we d...
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