Abstract Background and Aims Kidney is a high energy-consuming organ depending on fatty acid β-oxidation (FAO) to fulfil energy supply. During various biological stresses in AKI, FAO shuts down, the aerobic glycolysis enhanced. In this study, we aimed investigate effect of local lactate production AKI. Methods & Results A maleic (MA) induced AKI model (MA-AKI) was established by MA intraper...
