Traditionally, integration has been studied at the country level. With increasing economic integration, industrial reorganization, and blurring of national boundaries (e.g., EU), it is important to investigate global integration at the industry level. We argue that country-level integration (segmentation) does not preclude industry-level segmentation (integration). Indeed, our results suggest t...

The aim of this paper is to expand the methodological spectrum of socially responsible investing by introducing stochastic sustainability returns into safety first models for portfolio choice. We provide a foundation of the notion of sustainability in portfolio theory and establish a general model for generalized safety first portfolio management with probabilistic constraints and three special...

Using Web-of-Science data, portfolio analysis in terms of journal coverage can be projected on a base map for units of analysis such as countries, cities, universities, and firms. The units of analysis under study can be compared statistically across the 10,000+ journals. The interdisciplinarity of the portfolios is measured using Rao-Stirling diversity or Zhang et al.’s (in press) improved mea...

Are animals conscious? If so, when did consciousness evolve? We address these long-standing and essential questions using a modern neuroscientific approach that draws on diverse fields such as consciousness studies, evolutionary neurobiology, animal psychology, and anesthesiology. We propose that the stepwise emergence from general anesthesia can serve as a reproducible model to study the evolu...

Local anesthetics, on the other hand, deposited near a nerve between the surgical site and the brain, set up a chemical roadblock that prevents the pain impulse from ever reaching the brain (Figure 1). The patient’s level of consciousness remains unaffected when local anesthetics are administered, unlike the CNS depressants used in general anesthesia. The safety of local anesthetics may be garn...

Obstetric anesthesiology is a significant component of modern anesthesiology, and a high risk sub-specialty because of its involvement of both mother and newborn. Having a late start, obstetric anesthesiology in mainland China has been developing synchronously with all other anesthesiology sub-specialties. Advances in science and technology and improvement of management skills in recent decades...

How does general anesthesia (GA) work? Anesthetics are pharmacological agents that target specific central nervous system receptors. Once they bind to their brain receptors, anesthetics modulate remote brain areas and end up interfering with global neuronal networks, leading to a controlled and reversible loss of consciousness. This remarkable manipulation of consciousness allows millions of pe...

PURPOSE OF REVIEW Clinical practices in oxygen administration are in need of change based on the increasing understanding of oxygen toxicity. Hypoxemia is due to many pathophysiological causes; avoiding hypoxemia is an important objective during neonatal anesthesia. Nevertheless, the only known cause for hyperoxemia is the excess and unnecessary administration of oxygen by healthcare providers....