نتایج جستجو برای: peak and trough levels
تعداد نتایج: 16881220 فیلتر نتایج به سال:
The objectives of this study were to (i) construct a population pharmacokinetic (PK) model able to describe vancomycin (VAN) concentrations in serum in pediatric patients, (ii) determine VAN PK parameters in this population, and (iii) validate the predictive ability of this model in a naive pediatric population. Data used in this study were obtained from 78 pediatric patients (under 18 years ol...
Using fluorescence polarization immunoassay, we measured the peak and trough concentrations of total and free carbamazepine in serum and saliva from 33 epileptic children. We found that, except for patients who show side effects, measurement of trough values in a single sample, collected after an overnight fast and before the morning dose, sufficiently estimates clinical response. Moreover, tot...
BACKGROUND Unlike other respiratory infections, tuberculosis diagnoses increase in summer. We performed an ecological analysis of this paradoxical seasonality in a Peruvian shantytown over 4 years. METHODS Tuberculosis symptom-onset and diagnosis dates were recorded for 852 patients. Their tuberculosis-exposed cohabitants were tested for tuberculosis infection with the tuberculin skin test (n...
this study investigated the functions, types and frequencies of code switching in the teachers and students discourse in elt classrooms. to this end, the participants of this study including two groups of teachers and students were selected. the first group of participants were two efl teachers teaching general english courses (at two different levels of proficiency) in an institutional program...
We introduce random evolving lotteries to study preference for non‐instrumental information. Each period, the agent enjoys a flow payoff from holding lottery that will resolve at terminal date. provide representation theorem non‐separable risk consumption preferences and use it characterize agents' attitude To address applications, we peak‐trough utilities aggregate trajectories of linearly but...
Sir, Previous studies in a rabbit model of staphylococcal endo-carditis have demonstrated significant antibacterial effects with the oxazolidinone linezolid. 1,2 In those studies, increases in peak and trough linezolid plasma levels were noted between the first and final doses of the 5 day treatment period. We report results of additional studies to determine the effects of treatment duration o...
BACKGROUND Although vancomycin is frequently used to treat neonatal late-onset sepsis, there is no consensus on the optimal dosing regimen. Because many neonates needed dosing adaptation due to suboptimal trough values, the vancomycin dosing regimen in our neonatal department was changed during 2012. OBJECTIVE We aimed to document the need for validation of neonatal vancomycin dosing by explo...
abstract this thesis includes five chapter : the first chapter assign to establish fuzzy mathematics requirement and introduction of liner programming in thesis. the second chapter we introduce a multilevel linear programming problems. the third chapter we proposed interactive fuzzy programming which consists of two phases , the study termination conditions of algorithm we show a satisfac...
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