نتایج جستجو برای: proliferation index
تعداد نتایج: 573601 فیلتر نتایج به سال:
BACKGROUND The aim was to confirm a previously defined prognostic index, combining a proliferation marker, histological grade, and estrogen receptor (ER) in different subsets of primary N0/N1 chemo-naïve breast cancer patients. METHODSDESIGN In the present study, including 1,854 patients, Ki67 was used in the index (KiGE), since it is the generally accepted proliferation marker in clinical ro...
در سراسر دنیا بیش از 500 میلیون نفر به هپاتیتهای b و c مبتلا هستند. حتی گزارشاتی مبنی بر ابتلای افراد واکسینه به هپاتیت b نیز در نقاط مختلف وجود دارد. از طرفی با توجه به اینکه واکسن مناسبی بر علیه هپاتیت c وجود نداشته و یکی از مسائل مهم در پروژه واکسن ، یافتن ادجوانتی موثر و مناسب در واکسنهای انسانی است ،در این تحقیق خاصیت چپرونی و ادجوانتی پروتئین ساب یونیت بتایhsp90 انسانی مورد بررسی قرار گرف...
We showed that guaraná (Paullinia cupana Mart var. sorbilis) had a chemopreventive effect on mouse hepatocarcinogenesis and reduced diethylnitrosamine-induced DNA damage. In the present experiment, we evaluated the effects of guaraná in an experimental metastasis model. Cultured B16/F10 melanoma cells (5 x 10(5) cells/animal) were injected into the tail vein of mice on the 7th day of guaraná tr...
BACKGROUND The evaluation of intestinal trophism, mainly the mucosal layer, is an important issue in various conditions associated with injury, atrophy, recovery, and healing of the gut. The aim of the present study was to evaluate the kinetics of the proliferation and apoptosis of enterocytes by immunohistochemistry and to assess the complexity of intestinal mucosa by fractal dimension (FD) an...
The expression of proliferating cell nuclear antigen (PCNA) correlates to cell proliferation and for this reason it is commonly considered as one of proliferation markers. Since proliferation rate is an important factor determining the tumor aggressiveness, the evaluation of PCNA index (the percentage of PCNA-immunopositive nuclei in the investigated tumor sample) is suggested as useful in pred...
Cell proliferation assays are performed using antibodies against nuclear proteins associated with DNA replication. These nuclear proteins have gained special interest to predict the biological and clinical behaviors of various tumors. The aim of this study was to analyze the presence of Ki-67 protein and the minichromosome maintenance-2 (MCM2) and maintenance-3 (MCM3) proteins in ameloblastoma....
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