Articular cartilage degeneration represents one of the main features osteoarthritis. Recently, novel approaches based on biomaterials have been successfully applied to osteochondral regeneration. Our study was carried out rabbits assess a model articular damage test for We created defects surface trochlear groove area femurs in 15 white male New Zealand size 3 mm × (diameter depth). Rabbits wer...

background: considering the common origin of skin and peripheral nervous system, a tube of dermal layer of skin hypothetically can be an ideal conduit for nerve reconstruction. an experimental study performed to evaluate the nerve regeneration of efficacy into a dermal tube. methods: sixty male wistar rats were used. a 10 mm gap was produced in right sciatic nerves. in group a the autogenous ne...

Objective(s): In order to evaluate the effect of post-reconstruction Gaussian filtering on image quality and myocardial blood flow (MBF) measurement by dynamic N-13 ammonia positron emission tomography (PET), we compared various reconstruction and filtering methods with image characteristics. Methods: Dynamic PET images of three patients with coronary artery disease (male-female ratio of 2:1; a...

Diseases and defects of the temporomandibular joint (TMJ), compromising the cartilaginous layer of the condyle, impose a significant treatment challenge. Different regeneration approaches, especially surgical interventions at the TMJ's cartilage surface, are established treatment methods in maxillofacial surgery but fail to induce a regeneration ad integrum. Cartilage tissue engineering, in con...

Organ regeneration is becoming a promising choice for many patients; however, many details about the mechanisms underlying organ regeneration remain unknown. As regenerative organs, hair follicles offer a good model to study the mechanisms associated with regenerative medicine. The relevant studies have mainly focused on donor cells, and there are no systematic studies involving the effect of h...

Among the various methods of mandibular reconstruction, regeneration using poly-L-lactic acid mesh and particulate cancellous bone and marrow attained good efficacy and safety in a multi-institution prospective clinical study in Japan (Project No. GM941). This mandibular reconstruction method is not difficult to perform and is minimally invasive to the patient. If the use of this surgical techn...