in the present study, floating drug delivery beads (fdds) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. in order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the consti...

the present study describes the encapsulation of protocorm of cymbidium bicolor lindl. from 60 days-old in seed cultures for short- term conservation and propagation. various concentrations and combinations of gelling matrix (sodium alginate) and complexing agents (calcium chloride) were tested to prepare uniform beads. the ideal beads were ob- tained through a combination of 3% sodium alginate...

the purpose of the research was to formulate microspheres of acyclovir (acv) using mucoadhesive polymers, sodium alginate and chitosan. calcium chloride was used as the ionotropic gelling agent. sodium alginate was crosslinked by calcium chloride leading to a slower release of the drug. chitosan which is a cationic polymer interacted with sodium alginate, an anionic polymer, to form an interpol...

Purpose: Psylliumseeds are used in traditional herbal medicine to treat various disorders. Moreover, as a soluble fiber, psyllium has potential to stimulate bacterial growth in digestive system. We aimed to substitute alkali-extractable polysaccharides of psyllium for alginate in beads with second coat of poly-l-lysine to coat Lactobacillus acidophilus. Methods: Beads were prepared using extrus...

The purpose of this study was to evaluate the effects of alginate composition on the neurotrophic factor release, viability, and proliferation of encapsulated neural stem cells (NSCs), as well as on the mechanical stability of the scaffold itself. Four compositions were tested: a high guluronic acid (68%) and a high mannuronic acid (54%) content alginate, with or without a poly-L-lysine (PLL) c...

Objective(s):   The production of nano-hydroxyapatite by two encapsulated bacterial strains was the goal of current research.  Materials and Methods:   Serratia marcscens ATCC 14756 and Pseudomonas aeruginosa PTCC 1570 were used by two methods including encapsulated form in 2% (w/v) alginate sodium powder and inoculated form (10%) in nutrient broth medium containing alginate sodium blank beads....

This study was supported by EU FP7 grant GlowBrain (REGPOT–2012–CT2012– 316120) to S.G. and by a University of Trento Startup Grant and the Cassa di Risparmio di Trento e Rovereto Grant n. 2011.0251 to S.C. Since the central nervous system shows very little capability for self-repair following ischemic injury, regenerative medicine approaches are increasingly interested in the use of neural ste...

The aim of this study was to investigate the effects of Sodiume alginate edible coating with concentrations of 0/25, 1/25, 0/75 and 1/75% (W/V) on chemical changes of dressed Kilka during frozen storage. Prepared samples of Kilka fish have been coated for 1 h with the dipping method. Coated and uncoated samples have been packed in polyethylene dishes with selphon coverage (75 packs of 250 g). C...

Background: Magnetic nanoparticles (MNPs) loaded by various active compounds can be used for targeted drug delivery.Objectives: In the present study, the Fe3O4 magnetic nanoparticles that contained gentamicin were prepared and their antibacterial activities were studied.Materials and Methods: MNPs containing gentamicin (G@SA-MNPs) w...