Nowadays, in the clinic routine, protein biomarkers of efficacy, or mode of action, are used to better monitor and predict patient responses to drug treatment and diagnosis. Currently, the chemiluminescence biomarkers are applied for validation methods and screening. Here, was revised the development of the new analytical tool through immunological (antibody) and chemiluminescent methods combin...

background: liver cirrhosis was one of the most important liver diseases. other chronic liver diseases could be lead to liver cirrhosis. liver cirrhosis could be lead one kind of liver cancers named hepatocellular carcinoma. cirrhosis in the early stages just by laboratory and imaging testes could be diagnosed. in this study cirrhotic patients were classified based on laboratory symptoms. for t...

A review of the mechanisms of speciation is performed. The mechanisms of the evolution of species, taking into account the feedback of the state of the environment and mechanisms of the emergence of complexity, are considered. It is shown that these mechanisms, at the molecular level, cannot work steadily in terms of classical mechanics. Quantum mechanisms of changes in the genome, based on the...

BACKGROUND Bio-entity extraction is a pivotal component for information extraction from biomedical literature. The dictionary-based bio-entity extraction is the first generation of Named Entity Recognition (NER) techniques. METHODS This paper presents a hybrid dictionary-based bio-entity extraction technique. The approach expands the bio-entity dictionary by combining different data sources a...