AN INVESTIGATION INTO THE PHYSIOLOGICAL ROLE OFANNEXIN A11 A. Tomas and S.E. MossDivision of Cell Biology, Institute of Ophthalmology, University College London, London (UK) Annexin A11 is a calcium-dependent phospholipid-binding protein that interacts in vitro with the EF-hand protein, Calcyclin. It is broadly distributed and has the longestN-terminal domain (197 aa) of all known a...

acid (EPA, 20 :5, n-3). In this study, we inyestigated the interaction of sesamin and EPA on A5 desaturation of both series and the n-61n-3 fatty acids ratio by measuring actural fatty acid contents in vivo. Rats vvere fed three types of dietary oils; 1) lino]eic a id (LA, 18:2, n-6); linolenic a id (LLA, 18:3, n-3)= 3:1, n-61n-3 ratio of 3:1 (LA group), 2) LA:LLA =1:3, n-6fn-3 ratio of 1:3 (LL...

acid (EPA, 20 :5, n-3). In this study, we inyestigated the interaction of sesamin and EPA on A5 desaturation of both series and the n-61n-3 fatty acids ratio by measuring actural fatty acid contents in vivo. Rats vvere fed three types of dietary oils; 1) lino]eic a id (LA, 18:2, n-6); linolenic a id (LLA, 18:3, n-3)= 3:1, n-61n-3 ratio of 3:1 (LA group), 2) LA:LLA =1:3, n-6fn-3 ratio of 1:3 (LL...

Annexin A5 is a Ca2+-dependent phospholipid binding protein well known for its high phosphatidylserine affinity. In vitro, translocation to sarcolemma and externalization of endogenous annexin A5 in the cardiomyocyte has recently been demonstrated to exert a proapoptotic effect. To determine whether these in vitro findings occurred in vivo, we performed myocardial infarction (MI) and studied th...

Mangrove is an important ecosystem in the world. Mangrove ecosystems have a large capacity in retaining heavy metals, and now they are usually considered as sinks for heavy metals. However, the mechanism of why the soil of mangrove ecosystems can retain heavy metal is not certain. In this research, endophytic fungus Purpureocillium sp. A5 was isolated and identified from the roots of Kandelia c...

Laminins are extracellular matrix glycoproteins that influence the phenotype and functions of many types of cells. Laminins are heterotrimers composed of a, b, and g polypeptides. So far five a, three b, and two g polypeptide chains, and 11 variants of laminins have been proposed. Laminins interact in vitro with mature blood cells and malignant hematopoietic cells. Most studies have been perfor...