A major obstacle to the development of effective treatment of Alzheimer's disease (AD) is successfully delivery of drugs to the brain. We have previously identified a series of benzothiazole phosphonate compounds that block the interaction of amyloid-β peptide with amyloid-β binding alcohol dehydrogenase (ABAD). A selective and sensitive method for the presence of three new benzothiazole ABAD i...

Current strategies for the treatment of Alzheimer's disease (AD) involve tackling the formation or clearance of the amyloid-beta peptide (Aβ) and/or hyper-phosphorylated tau, or the support and stabilization of the remaining neuronal networks. However, as we gain a clearer idea of the large number of molecular mechanisms at work in this disease, it is becoming clearer that the treatment of AD s...

INTRODUCTION The present study which is carried out in the field of medical anthropology seeks to investigate the meaningful medical behaviors of people with diabetes living in the village of Koohzar have taken to improve or reduce the problems associated with the disease regarding to knowledge and resources available in the country. MATERIAL AND METHODS Field and in-depth study are used as r...

The Egypt Human Development Report 2003 does not take account of the impact of the environment on human development indicators. A case study was made in one village in El-Montaza district, Alexandria governorate, Egypt. The environmental indicators used for calculating the human development index were access to safe water, access to sanitation and environment surrounding the house. The human de...

As a development form of the creative industry, Artist Village is high concern Chinese government, and it has achieved rapid developments in China recent years. However, many Villages come to an untimely end short period after their birth fail realize sustainable development. In this study, empirical analysis on 80 was carried out. A field investigation research eight implemented. Attention pai...

BACKGROUND Chagas disease is a major neglected tropical disease with deep socio-economical effects throughout Central and South America. Vector control programs have consistently reduced domestic populations of triatomine vectors, but non-domiciliated vectors still have to be controlled efficiently. Designing control strategies targeting these vectors is challenging, as it requires a quantitati...