Platelet parameters such as Mean platelet volume (MPV) and Platelet distribution width (PDW) are indicators of platelet activation. In cases with Rheumatoid arthritis inflammatory markers such as C-reactive protein and Erythrocyte sedimentation Rate are affected .Studies have pointed out the occurrence of changes in platelet counts in acute stages of Rheumatoid arthritis, the cause being platel...

OBJECTIVE To investigate whether oestrogens can be used as treatment to diminish disease activity in women with rheumatoid arthritis. METHODS Forty postmenopausal female patients with active rheumatoid arthritis participated in a placebo-controlled, double-blind study on the possible beneficial effect of adjuvant treatment of oestradiol on disease activity. RESULTS Thirty three patients com...

As demonstrated by various investigators (Carter and Maclagan, 1946; Stillerman, 1948; Poulsen, 1949; Kalbak, 1951), the thymol reaction is positive in rheumatoid arthritis patients at a somewhat advanced and active stage of the disease. This positive reaction is assumed to be due to changes in the serum proteins. Patients with rheumatoid arthritis generally show marked changes in the serum pro...

In an attempt to define the immunoregulatory mechanisms operating in rheumatoid arthritis we have enumerated T cell subsets in the peripheral blood and synovial fluid of patients with this disease. The peripheral blood analysis revealed an elevation of the ratio of inducer T cells (OKT4 positive) to suppressor/cytotoxic T cells (OKT5 positive) in patients with clinically active rheumatoid arthr...

A 44 year old white woman with rheumatoid arthritis for 19 years developed subcorneal pustular dermatosis. She had increased polyclonal IgA and IgA rheumatoid factor. After 4 months' treatment with dapsone 100 mg daily the patient had neither skin lesions nor active joint disease.

Rheumatoid arthritis is a crippling disease that is often associated with severe pain, suffering, and diminished function, thereby detracting from an optimal quality of life. Over the past decade a greater appreciation of the pathophysiology of rheumatoid arthritis has been gained. In the past "decade of pain research," biologic agents which may modify rheumatoid arthritis have emerged as poten...

OBJECTIVE To test whether elevated concentration of rheumatoid factor is associated with long term development of rheumatoid arthritis. DESIGN A prospective cohort study, the Copenhagen City Heart Study. Blood was drawn in 1981-83, and participants were followed until 10 August 2010. SETTING Copenhagen general population. PARTICIPANTS 9712 white Danish individuals from the general populat...

Introduction: The aim of the present study was to compare the videolaryngostroboscopic findings between patients with rheumatoid arthritis and vocally healthy controls.   Materials and Methods: This case-control descriptive study was performed on 113 people, including 50 patients with rheumatoid arthritis and 63 controls. The participants were subjected to videolaryngost...